RAB40C Antibody - #DF9832
| Product: | RAB40C Antibody |
| Catalog: | DF9832 |
| Description: | Rabbit polyclonal antibody to RAB40C |
| Application: | WB IF/ICC |
| Reactivity: | Human, Mouse, Rat, Monkey |
| Prediction: | Pig, Zebrafish, Bovine, Horse, Sheep, Chicken, Xenopus |
| Mol.Wt.: | 31 kDa,38kDa; 31kD(Calculated). |
| Uniprot: | Q96S21 |
| RRID: | AB_2843026 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF9832, RRID:AB_2843026.
Fold/Unfold
rab 40C; Rab40c; RAB40C, member RAS oncogene family; RAR (RAS like GTPASE) like; RAR like; Rar like protein; Rar-like protein; RARL; RAS like GTPase; Ras like protein family member 8C; RAS like, family 8, member C; Ras related protein Rab40C; Ras-like protein family member 8C; Ras-related protein Rab-40C; RASL8C; RB40C_HUMAN; SOCS box containing protein RAR3; SOCS box-containing protein RAR3;
Immunogens
- Q96S21 RB40C_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGSQGSPVKSYDYLLKFLLVGDSDVGKGEILESLQDGAAESPYAYSNGIDYKTTTILLDGRRVKLELWDTSGQGRFCTIFRSYSRGAQGILLVYDITNRWSFDGIDRWIKEIDEHAPGVPRILVGNRLHLAFKRQVPTEQARAYAEKNCMTFFEVSPLCNFNVIESFTELSRIVLMRHGMEKIWRPNRVFSLQDLCCRAIVSCTPVHLIDKLPLPVTIKSHLKSFSMANGMNAVMMHGRSYSLASGAGGGGSKGNSLKRSKSIRPPQSPPQNCSRSNCKIS
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q96S21 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S6 | Phosphorylation | Uniprot | |
| K133 | Ubiquitination | Uniprot | |
| K211 | Ubiquitination | Uniprot | |
| S240 | Phosphorylation | Uniprot | |
| S242 | Phosphorylation | Uniprot | |
| S252 | Phosphorylation | Uniprot | |
| S256 | Phosphorylation | Uniprot | |
| S262 | Phosphorylation | Uniprot | |
| S268 | Phosphorylation | Uniprot |
Research Backgrounds
Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Cell membrane>Lipid-anchor>Cytoplasmic side.
Component of the probable SCF-like ECS(RAB40C) E3 ubiquitin-protein ligase complex which contains CUL5, RNF7/RBX2, Elongin BC complex and RAB40C. Interacts with CUL5, RNF7, ELOB and ELOC.
The SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3 ubiquitin ligase complexes.
Belongs to the small GTPase superfamily. Rab family.
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