RAB40A/L Antibody - #DF9831
| Product: | RAB40A/L Antibody |
| Catalog: | DF9831 |
| Description: | Rabbit polyclonal antibody to RAB40A/L |
| Application: | WB IHC |
| Reactivity: | Human |
| Mol.Wt.: | 31 kDa; 31kD(Calculated). |
| Uniprot: | P0C0E4 | Q8WXH6 |
| RRID: | AB_2843025 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF9831, RRID:AB_2843025.
Fold/Unfold
MGC142061; Protein Rar 2; Protein Rar-2; RAB40A; RAB40A, member RAS oncogene family; Rar 2; RAR2A; Ras related protein Rab 40A; Ras-related protein Rab-40A; RB40A_HUMAN; SOCS box containing protein RAR2A; SOCS box-containing protein RAR2A;
Immunogens
Expressed in brain, lung, heart, skeletal muscle, kidney and liver. Highest expression in brain. Expressed in fetal brain and kidney.
- P0C0E4 RB40L_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSAPGSPDQAYDFLLKFLLVGDRDVGKSEILESLQDGTAESPYSHLGGIDYKTTTILLDGQRVKLKLWDTSGQGRFCTIFRSYSRGAQGVILVYDIANRWSFEGMDRWIKKIEEHAPGVPKILVGNRLHLAFKRQVPREQAQAYAERLGVTFFEVSPLCNFNIIESFTELARIVLLRHRLNWLGRPSKVLSLQDLCCRTIVSCTPVHLVDKLPLPIALRSHLKSFSMAKGLNARMMRGLSYSLTTSSTHKRSSLCKVKIVCPPQSPPKNCTRNSCKIS
- Q8WXH6 RB40A_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSAPGSPDQAYDFLLKFLLVGDRDVGKSEILESLQDGAAESPYSHLGGIDYKTTTILLDGQRVKLKLWDTSGQGRFCTIFRSYSRGAQGVILVYDIANRWSFEGMDRWIKKIEEHAPGVPKILVGNRLHLAFKRQVPREQAQAYAERLGVTFFEVSPLCNFNIIESFTELARIVLLRHRMNWLGRPSKVLSLQDLCCRTIVSCTPVHLVDKLPLPSTLRSHLKSFSMAKGLNARMMRGLSYSLTTSSTHKSSLCKVEIVCPPQSPPKNCTRNSCKIS
PTMs - P0C0E4/Q8WXH6 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S28 | Phosphorylation | Uniprot | |
| K133 | Ubiquitination | Uniprot | |
| S247 | Phosphorylation | Uniprot |
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K133 | Ubiquitination | Uniprot | |
| S264 | Phosphorylation | Uniprot |
Research Backgrounds
May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Membrane>Lipid-anchor>Cytoplasmic side. Cytoplasm. Mitochondrion.
Expressed in brain, lung, heart, skeletal muscle, kidney and liver. Highest expression in brain. Expressed in fetal brain and kidney.
The SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3 ubiquitin ligase complexes.
Belongs to the small GTPase superfamily. Rab family.
May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Cell membrane>Lipid-anchor>Cytoplasmic side.
The SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3 ubiquitin ligase complexes.
Belongs to the small GTPase superfamily. Rab family.
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