RASGEF1B Antibody - #DF9808
| Product: | RASGEF1B Antibody |
| Catalog: | DF9808 |
| Description: | Rabbit polyclonal antibody to RASGEF1B |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus |
| Mol.Wt.: | 55 kDa; 55kD(Calculated). |
| Uniprot: | Q0VAM2 |
| RRID: | AB_2843002 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF9808, RRID:AB_2843002.
Fold/Unfold
FLJ31695; GPI gamma-4; GPIG4; MGC46251; Ras-GEF domain-containing family member 1B; RasGEF domain family member 1B; RASGEF1B; RGF1B_HUMAN;
Immunogens
- Q0VAM2 RGF1B_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MPQTPPFSAMFDSSGYNRNLYQSAEDSCGGLYYHDNNLLSGSLEALIQHLVPNVDYYPDRTYIFTFLLSSRLFMHPYELMAKVCHLCVEHQRLSDPDSDKNQMRKIAPKILQLLTEWTETFPYDFRDERMMRNLKDLAHRIASGEEQTYRKNVQQMMQCLIRKLAALSQYEEVLAKISSTSTDRLTVLKTKPQSIQRDIITVCNDPYTLAQQLTHIELERLNYIGPEEFVQAFVQKDPLDNDKSCYSERKKTRNLEAYVEWFNRLSYLVATEICMPVKKKHRARMIEYFIDVARECFNIGNFNSLMAIISGMNMSPVSRLKKTWAKVKTAKFDILEHQMDPSSNFYNYRTALRGAAQRSLTAHSSREKIVIPFFSLLIKDIYFLNEGCANRLPNGHVNFEKFWELAKQVSEFMTWKQVECPFERDRKILQYLLTVPVFSEDALYLASYESEGPENHIEKDRWKSLRSSLLGRV
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q0VAM2 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y77 | Phosphorylation | Uniprot | |
| Y149 | Phosphorylation | Uniprot | |
| S266 | Phosphorylation | Uniprot | |
| Y267 | Phosphorylation | Uniprot | |
| T271 | Phosphorylation | Uniprot | |
| T323 | Phosphorylation | Uniprot |
Research Backgrounds
Guanine nucleotide exchange factor (GEF) with specificity for RAP2A, it doesn't seems to activate other Ras family proteins (in vitro).
Early endosome. Late endosome. Midbody.
Note: May shuttle between early and late endosomes (By similarity). Localizes to midbody at telophase.
Interacts with Ras family proteins (By similarity). Interacts with CCDC124 during cytokinesis.
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