RFTN2 Antibody - #DF9799
(1)
| Product: | RFTN2 Antibody |
| Catalog: | DF9799 |
| Description: | Rabbit polyclonal antibody to RFTN2 |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Mol.Wt.: | 56 kDa; 56kD(Calculated). |
| Uniprot: | Q52LD8 |
| RRID: | AB_2842993 |
Related Downloads
Protocols
Product Info
Source:
Rabbit
Application:
WB 1:1000-3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Reactivity:
Human,Mouse,Rat
Clonality:
Polyclonal
Specificity:
RFTN2 Antibody detects endogenous levels of total RFTN2.
RRID:
AB_2842993
Cite Format: Affinity Biosciences Cat# DF9799, RRID:AB_2842993.
Cite Format: Affinity Biosciences Cat# DF9799, RRID:AB_2842993.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:
Fold/Unfold
Raft-linking protein 2; Raftlin-2; Rftn2; RFTN2_HUMAN;
Immunogens
Immunogen:
Uniprot:
Gene(ID):
Sequence:
- Q52LD8 RFTN2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGCGLRKLEDPDDSSPGKIFSTLKRPQVETKTEFAYEYVLLDFTLQASSNPEVIKINSILDIVTKVENYYLKGYIVGAIHPVIQPVGQRKHLPASYLYRVVLLRLKLSPKNSAAPSGQRRPRLVIEECPLTSEAQTNDAAKELIEKINVAAKRGMKFVGFISQHYSPSKFCNGTNHDGDIESMLHVRHGSDENCRSWNEGTLSGQSSESGIEEELHHESGQYQMEQNGSPTSSKSRKGEASDNKLYTVFNAFDDDSTSWAYQEGILSMKVTRKGSVISTLDADWLELTTFYYKQGLSLIDSFVFWETSKGEHLPKSLEGFFIYEEEGSGVPGSSRKGNDAIVVEQWTVIEGCEIKTDYGPLLHTLAEFGWLLTSVLPTPVLRHDSEGNLATKQIVFLQRPVMWNSAAQTPDKKASRHIKGEDKNKATSRSIGLDTTSSQPAESRHLPEECRLSPSRECWTKEGRLAQHNSFSGFSSSDNVLRELDDGQFDQEDGVTQVTCM
PTMs - Q52LD8 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y222 | Phosphorylation | Uniprot | |
| S235 | Phosphorylation | Uniprot | |
| Y323 | Phosphorylation | Uniprot | |
| S334 | Phosphorylation | Uniprot | |
| T409 | Phosphorylation | Uniprot | |
| T427 | Phosphorylation | Uniprot | |
| S430 | Phosphorylation | Uniprot | |
| T436 | Phosphorylation | Uniprot | |
| S438 | Phosphorylation | Uniprot | |
| S443 | Phosphorylation | Uniprot | |
| S455 | Phosphorylation | Uniprot | |
| S470 | Phosphorylation | Uniprot | |
| S472 | Phosphorylation | Uniprot |
Research Backgrounds
Function:
Upon bacterial lipopolysaccharide stimulation, mediates clathrin-dependent internalization of TLR4 in dendritic cells, resulting in activation of TICAM1-mediated signaling and subsequent IFNB1 production. May regulate B-cell antigen receptor-mediated signaling.
Subcellular Location:
Cell membrane>Lipid-anchor.
Family&Domains:
Belongs to the raftlin family.
Restrictive clause
Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.
For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.