PDP1 Antibody - #DF9794

(1)  
Product: PDP1 Antibody
Catalog: DF9794
Description: Rabbit polyclonal antibody to PDP1
Application: WB
Reactivity: Human, Mouse, Rat
Prediction: Pig, Zebrafish, Bovine, Sheep, Dog, Chicken, Xenopus
Mol.Wt.: 61 kDa; 61kD(Calculated).
Uniprot: Q9P0J1
RRID: AB_2842988

View similar products>>

   Size Price Inventory
 100ul $280 In stock
 200ul $350 In stock

Lead Time: Same day delivery

For pricing and ordering contact:
Local distributors
Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Pig(100%), Zebrafish(80%), Bovine(100%), Sheep(100%), Dog(100%), Chicken(100%), Xenopus(100%)
Clonality:
Polyclonal
Specificity:
PDP1 Antibody detects endogenous levels of total PDP1.
RRID:
AB_2842988
Cite Format: Affinity Biosciences Cat# DF9794, RRID:AB_2842988.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

[Pyruvate dehydrogenase [acetyl transferring]] phosphatase 1, mitochondrial; [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1; FLJ32517; Gm1024; MGC119646; mitochondrial; PDH; PDP 1; PDP; Pdp1; PDP1_HUMAN; PDPC 1; PDPC; PPM2C; Protein phosphatase 2C; protein phosphatase 2C, magnesium dependent, catalytic subunit; Pyruvate dehydrogenase (Lipoamide) phosphatase phosphatase; Pyruvate dehydrogenase phosphatase catalytic subunit 1; Pyruvate dehydrogenase phosphatase, catalytic subunit 1; RP23 203A12.1;

Immunogens

Immunogen:
Uniprot:

Q9P0J1(PDP1_HUMAN) >>Visit HPA database.

Gene(ID):
PDP1(54704)
Sequence:
MPAPTQLFFPLIRNCELSRIYGTACYCHHKHLCCSSSYIPQSRLRYTPHPAYATFCRPKENWWQYTQGRRYASTPQKFYLTPPQVNSILKANEYSFKVPEFDGKNVSSILGFDSNQLPANAPIEDRRSAATCLQTRGMLLGVFDGHAGCACSQAVSERLFYYIAVSLLPHETLLEIENAVESGRALLPILQWHKHPNDYFSKEASKLYFNSLRTYWQELIDLNTGESTDIDVKEALINAFKRLDNDISLEAQVGDPNSFLNYLVLRVAFSGATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEHPKSEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNYHTPPYLTAEPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVRIVGEYLTGMHHQQPIAVGGYKVTLGQMHGLLTERRTKMSSVFEDQNAATHLIRHAVGNNEFGTVDHERLSKMLSLPEELARMYRDDITIIVVQFNSHVVGAYQNQE

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Bovine
100
Sheep
100
Dog
100
Xenopus
100
Chicken
100
Zebrafish
80
Horse
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9P0J1 As Substrate

Site PTM Type Enzyme
R43 Methylation
Y46 Phosphorylation
K59 Ubiquitination
K77 Ubiquitination
Y79 Phosphorylation
K90 Ubiquitination
Y94 Phosphorylation
K97 Ubiquitination
K104 Acetylation
K104 Ubiquitination
K194 Ubiquitination
Y199 Phosphorylation
K202 Acetylation
K202 Ubiquitination
K206 Ubiquitination
K241 Acetylation
K241 Ubiquitination
K326 Acetylation
K326 Ubiquitination
K331 Acetylation
K331 Ubiquitination
K335 Acetylation
K335 Ubiquitination
K339 Ubiquitination
K357 Acetylation
K357 Ubiquitination
K359 Ubiquitination
K366 Sumoylation
K366 Ubiquitination
Y381 Phosphorylation P00533 (EGFR) , P11362 (FGFR1)
K383 Ubiquitination
K411 Ubiquitination
K452 Ubiquitination
K468 Acetylation
K468 Ubiquitination
K502 Acetylation
K502 Ubiquitination

Research Backgrounds

Function:

Catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex.

Subcellular Location:

Mitochondrion matrix.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Subunit Structure:

Heterodimer of a catalytic (PDP1) and a regulatory (PDPR) subunit.

Family&Domains:

Belongs to the PP2C family.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.