PLSCR4 Antibody - #DF9756
| Product: | PLSCR4 Antibody |
| Catalog: | DF9756 |
| Description: | Rabbit polyclonal antibody to PLSCR4 |
| Application: | WB IF/ICC |
| Reactivity: | Human |
| Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| Mol.Wt.: | 37 kDa; 37kD(Calculated). |
| Uniprot: | Q9NRQ2 |
| RRID: | AB_2842951 |
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF9756, RRID:AB_2842951.
Fold/Unfold
AV245873; Ca(2+)-dependent phospholipid scramblase 4; Cell growth inhibiting protein 43; Cell growth-inhibiting gene 43 protein; GIG43; Phospholipid scramblase 4; PL scramblase 4; Pls4; PLS4_HUMAN; Plscr4; TRA1;
Immunogens
Expressed in heart, brain, placenta, lung, liver, kidney, pancreas, spleen, thymus, prostate, testis, uterus, small intestine and colon. Not detected in peripheral blood lymphocytes.
- Q9NRQ2 PLS4_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSGVVPTAPEQPAGEMENQTKPPDPRPDAPPEYNSHFLPGPPGTAVPPPTGYPGGLPMGYYSPQQPSTFPLYQPVGGIHPVRYQPGKYPMPNQSVPITWMPGPTPMANCPPGLEYLVQLDNIHVLQHFEPLEMMTCFETNNRYDIKNNSDQMVYIVTEDTDDFTRNAYRTLRPFVLRVTDCMGREIMTMQRPFRCTCCCFCCPSARQELEVQCPPGVTIGFVAEHWNLCRAVYSIQNEKKENVMRVRGPCSTYGCGSDSVFEVKSLDGISNIGSIIRKWNGLLSAMADADHFDIHFPLDLDVKMKAMIFGACFLIDFMYFERSPPQRSR
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9NRQ2 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y83 | Phosphorylation | A0A173G4P4 (Abl fusion) | Uniprot |
| Y88 | Phosphorylation | A0A173G4P4 (Abl fusion) | Uniprot |
| S234 | Phosphorylation | Uniprot |
Research Backgrounds
May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system.
Membrane>Single-pass type II membrane protein.
Expressed in heart, brain, placenta, lung, liver, kidney, pancreas, spleen, thymus, prostate, testis, uterus, small intestine and colon. Not detected in peripheral blood lymphocytes.
Interacts with PDCD6.
The N-terminal proline-rich domain (PRD) is required for phospholipid scramblase activity.
Belongs to the phospholipid scramblase family.
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