Product: PIGP Antibody
Catalog: DF9744
Description: Rabbit polyclonal antibody to PIGP
Application: WB IHC IF/ICC
Reactivity: Human, Mouse, Monkey
Prediction: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken
Mol.Wt.: 18 kDa; 18kD(Calculated).
Uniprot: P57054
RRID: AB_2842939

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 100ul $280 In stock
 200ul $350 In stock

Lead Time: Same day delivery

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Product Info

Source:
Rabbit
Application:
WB 1:1000-3000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Monkey
Prediction:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%), Chicken(100%)
Clonality:
Polyclonal
Specificity:
PIGP Antibody detects endogenous levels of total PIGP.
RRID:
AB_2842939
Cite Format: Affinity Biosciences Cat# DF9744, RRID:AB_2842939.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

DCRC; DCRC S; Down syndrome critical region gene 5; Down syndrome critical region protein 5; Down syndrome critical region protein C; DSCR 5; DSCR5; DSCRC; DSRC; Phosphatidylinositol glycan anchor biosynthesis class P; Phosphatidylinositol glycan biosynthesis class P; Phosphatidylinositol glycan biosynthesis class P protein; Phosphatidylinositol glycan class P; Phosphatidylinositol n acetylglucosaminyltranferase subunit; Phosphatidylinositol N acetylglucosaminyltransferase subunit P; Phosphatidylinositol N-acetylglucosaminyltransferase subunit P; Phosphatidylinositol-glycan biosynthesis class P protein; PIG-P; PIGP; PIGP_HUMAN;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
P57054 PIGP_HUMAN:

Ubiquitous.

Sequence:
MVPRSTSLTLIVFLFHRLSKAPGKMVENSPSPLPERAIYGFVLFLSSQFGFILYLVWAFIPESWLNSLGLTYWPQKYWAVALPVYLLIAIVIGYVLLFGINMMSTSPLDSIHTITDNYAKNQQQKKYQEEAIPALRDISISEVNQMFFLAAKELYTKN

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Chicken
100
Rabbit
100
Xenopus
78
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - P57054 As Substrate

Site PTM Type Enzyme
T6 Phosphorylation
T9 Phosphorylation
S19 Phosphorylation
K126 Ubiquitination
K157 Ubiquitination

Research Backgrounds

Function:

Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.

Subcellular Location:

Membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Ubiquitous.

Subunit Structure:

Associates with PIGA, PIGC, PIGH, PIGQ and DPM2. The latter is not essential for activity.

Family&Domains:

Belongs to the PIGP family.

Research Fields

· Metabolism > Glycan biosynthesis and metabolism > Glycosylphosphatidylinositol (GPI)-anchor biosynthesis.

· Metabolism > Global and overview maps > Metabolic pathways.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.