SC65 Antibody - #DF9715
| Product: | SC65 Antibody |
| Catalog: | DF9715 |
| Description: | Rabbit polyclonal antibody to SC65 |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Bovine, Sheep, Rabbit, Dog |
| Mol.Wt.: | 50 kDa; 50kD(Calculated). |
| Uniprot: | Q92791 |
| RRID: | AB_2842910 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF9715, RRID:AB_2842910.
Fold/Unfold
Leprecan-like protein 4; Leprel4; NOL55; Nucleolar autoantigen 55kDa; Nucleolar autoantigen No55; OTTHUMP00000164758; SC 65; SC65_HUMAN; Synaptonemal complex protein SC65;
Immunogens
Detected in fibroblasts (at protein level) (PubMed:23959653). Detected in spleen, prostate, testis, ovary, colon, pancreas, kidney, placenta and heart (PubMed:10952778).
- Q92791 SC65_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MARVAWGLLWLLLGSAGAQYEKYSFRGFPPEDLMPLAAAYGHALEQYEGESWRESARYLEAALRLHRLLRDSEAFCHANCSGPAPAAKPDPDGGRADEWACELRLFGRVLERAACLRRCKRTLPAFQVPYPPRQLLRDFQSRLPYQYLHYALFKANRLEKAVAAAYTFLQRNPKHELTAKYLNYYQGMLDVADESLTDLEAQPYEAVFLRAVKLYNSGDFRSSTEDMERALSEYLAVFARCLAGCEGAHEQVDFKDFYPAIADLFAESLQCKVDCEANLTPNVGGYFVDKFVATMYHYLQFAYYKLNDVRQAARSAASYMLFDPKDSVMQQNLVYYRFHRARWGLEEEDFQPREEAMLYHNQTAELRELLEFTHMYLQSDDEMELEETEPPLEPEDALSDAEFEGEGDYEEGMYADWWQEPDAKGDEAEAEPEPELA
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q92791 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y20 | Phosphorylation | Uniprot | |
| Y23 | Phosphorylation | Uniprot | |
| K160 | Ubiquitination | Uniprot | |
| K174 | Ubiquitination | Uniprot | |
| K213 | Ubiquitination | Uniprot | |
| Y234 | Phosphorylation | Uniprot |
Research Backgrounds
Part of a complex composed of PLOD1, P3H3 and P3H4 that catalyzes hydroxylation of lysine residues in collagen alpha chains and is required for normal assembly and cross-linking of collagen fibrils. Required for normal bone density and normal skin stability via its role in hydroxylation of lysine residues in collagen alpha chains and in collagen fibril assembly.
Endoplasmic reticulum.
Detected in fibroblasts (at protein level). Detected in spleen, prostate, testis, ovary, colon, pancreas, kidney, placenta and heart.
Interacts with PLOD1, P3H3 and PPIB. Identified in a complex with PLOD1 and P3H3.
Belongs to the leprecan family.
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