TNP2 Antibody - #DF9713
Product: | TNP2 Antibody |
Catalog: | DF9713 |
Description: | Rabbit polyclonal antibody to TNP2 |
Application: | WB IHC IF/ICC |
Reactivity: | Human |
Prediction: | Pig, Dog |
Mol.Wt.: | 16 kDa; 16kD(Calculated). |
Uniprot: | Q05952 |
RRID: | AB_2842908 |
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF9713, RRID:AB_2842908.
Fold/Unfold
Nuclear transition protein 2; TNP2; TP 2; TP2; Transition protein 2 (during histone to protamine replacement);
Immunogens
- Q05952 STP2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MDTQTHSLPITHTQLHSNSQPQSRTCTRHCQTFSQSCRQSHRGSRSQSSSQSPASHRNPTGAHSSSGHQSQSPNTSPPPKRHKKTMNSHHSPMRPTILHCRCPKNRKNLEGKLKKKKMAKRIQQVYKTKTRSSGWKSN
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q05952 As Substrate
Site | PTM Type | Enzyme | Source |
---|---|---|---|
S17 | Phosphorylation | Uniprot |
Research Backgrounds
Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction.
Nucleus. Chromosome.
Note: Loaded onto the nucleosomes of condensing spermatids (By similarity). Nuclear import is ATP-dependent and nucleolar localization requires the protein to be phosphorylated (By similarity).
Expressed by spermatids (at protein level).
Belongs to the nuclear transition protein 2 family.
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