NAV1 Antibody - #DF9694

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Product: NAV1 Antibody
Catalog: DF9694
Description: Rabbit polyclonal antibody to NAV1
Application: WB
Reactivity: Human, Mouse, Monkey
Prediction: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus
Mol.Wt.: 202 kDa; 202kD(Calculated).
Uniprot: Q8NEY1
RRID: AB_2842889

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 100ul $280 In stock
 200ul $350 In stock

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Monkey
Prediction:
Pig(100%), Bovine(82%), Horse(82%), Sheep(82%), Rabbit(100%), Dog(100%), Xenopus(80%)
Clonality:
Polyclonal
Specificity:
NAV1 Antibody detects endogenous levels of total NAV1.
RRID:
AB_2842889
Cite Format: Affinity Biosciences Cat# DF9694, RRID:AB_2842889.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

DKFZp781D0314; FLJ12560; FLJ14203; KIAA1151; MGC14961; mNav1; mouse Nav1; Nav 1; Nav1; neuron navigator 1; POMFIL 3; POMFIL3; Pore membrane and/or filament interacting like protein 3; Protein Steerin 1; Protein Steerin1; Steerin 1; Steerin1; unc-53 homolog 1; UNC53H1;

Immunogens

Immunogen:
Uniprot:

Q8NEY1(NAV1_HUMAN) >>Visit HPA database.

Gene(ID):
NAV1(89796)
Expression:
Q8NEY1 NAV1_HUMAN:

Broadly expressed at low levels. Expressed at high levels in heart, skeletal muscle and placenta.

Sequence:
MLGSSVKSVQPEVELSSGGGDEGADEPRGAGRKAAAADGRGMLPKRAKAPGGGGGMAKASAAELKVFKSGSVDSRVPGGPPASNLRKQKSLTNLSFLTDSEKKLQLYEPEWSDDMAKAPKGLGKVGSKGREAPLMSKTLSKSEHSLFQAKGSPAGGAKTPLAPLAPNLGKPSRIPRGPYAEVKPLSKAPEAAVSEDGKSDDELLSSKAKAQKSSGPVPSAKGQEERAFLKVDPELVVTVLGDLEQLLFSQMLDPESQRKRTVQNVLDLRQNLEETMSSLRGSQVTHSSLEMTCYDSDDANPRSVSSLSNRSSPLSWRYGQSSPRLQAGDAPSVGGSCRSEGTPAWYMHGERAHYSHTMPMRSPSKLSHISRLELVESLDSDEVDLKSGYMSDSDLMGKTMTEDDDITTGWDESSSISSGLSDASDNLSSEEFNASSSLNSLPSTPTASRRNSTIVLRTDSEKRSLAESGLSWFSESEEKAPKKLEYDSGSLKMEPGTSKWRRERPESCDDSSKGGELKKPISLGHPGSLKKGKTPPVAVTSPITHTAQSALKVAGKPEGKATDKGKLAVKNTGLQRSSSDAGRDRLSDAKKPPSGIARPSTSGSFGYKKPPPATGTATVMQTGGSATLSKIQKSSGIPVKPVNGRKTSLDVSNSAEPGFLAPGARSNIQYRSLPRPAKSSSMSVTGGRGGPRPVSSSIDPSLLSTKQGGLTPSRLKEPTKVASGRTTPAPVNQTDREKEKAKAKAVALDSDNISLKSIGSPESTPKNQASHPTATKLAELPPTPLRATAKSFVKPPSLANLDKVNSNSLDLPSSSDTTHASKVPDLHATSSASGGPLPSCFTPSPAPILNINSASFSQGLELMSGFSVPKETRMYPKLSGLHRSMESLQMPMSLPSAFPSSTPVPTPPAPPAAPTEEETEELTWSGSPRAGQLDSNQRDRNTLPKKGLRYQLQSQEETKERRHSHTIGGLPESDDQSELPSPPALPMSLSAKGQLTNIVSPTAATTPRITRSNSIPTHEAAFELYSGSQMGSTLSLAERPKGMIRSGSFRDPTDDVHGSVLSLASSASSTYSSAEERMQSEQIRKLRRELESSQEKVATLTSQLSANANLVAAFEQSLVNMTSRLRHLAETAEEKDTELLDLRETIDFLKKKNSEAQAVIQGALNASETTPKELRIKRQNSSDSISSLNSITSHSSIGSSKDADAKKKKKKSWVYELRSSFNKAFSIKKGPKSASSYSDIEEIATPDSSAPSSPKLQHGSTETASPSIKSSTSSSVGTDVTEGPAHPAPHTRLFHANEEEEPEKKEVSELRSELWEKEMKLTDIRLEALNSAHQLDQLRETMHNMQLEVDLLKAENDRLKVAPGPSSGSTPGQVPGSSALSSPRRSLGLALTHSFGPSLADTDLSPMDGISTCGPKEEVTLRVVVRMPPQHIIKGDLKQQEFFLGCSKVSGKVDWKMLDEAVFQVFKDYISKMDPASTLGLSTESIHGYSISHVKRVLDAEPPEMPPCRRGVNNISVSLKGLKEKCVDSLVFETLIPKPMMQHYISLLLKHRRLVLSGPSGTGKTYLTNRLAEYLVERSGREVTEGIVSTFNMHQQSCKDLQLYLSNLANQIDRETGIGDVPLVILLDDLSEAGSISELVNGALTCKYHKCPYIIGTTNQPVKMTPNHGLHLSFRMLTFSNNVEPANGFLVRYLRRKLVESDSDINANKEELLRVLDWVPKLWYHLHTFLEKHSTSDFLIGPCFFLSCPIGIEDFRTWFIDLWNNSIIPYLQEGAKDGIKVHGQKAAWEDPVEWVRDTLPWPSAQQDQSKLYHLPPPTVGPHSIASPPEDRTVKDSTPSSLDSDPLMAMLLKLQEAANYIESPDRETILDPNLQATL

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Dog
100
Rabbit
100
Horse
82
Bovine
82
Sheep
82
Xenopus
80
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q8NEY1 As Substrate

Site PTM Type Enzyme
M1 Acetylation
K48 Acetylation
K58 Acetylation
S90 Phosphorylation
T92 Phosphorylation
S95 Phosphorylation
S100 Phosphorylation
T138 Phosphorylation
S142 Phosphorylation
S145 Phosphorylation
S152 Phosphorylation
K158 Sumoylation
T159 Phosphorylation
S172 Phosphorylation
S186 Phosphorylation
S194 Phosphorylation
S199 Phosphorylation
S205 Phosphorylation
S282 Phosphorylation
S288 Phosphorylation
S296 Phosphorylation
S303 Phosphorylation
S305 Phosphorylation
S306 Phosphorylation
S308 Phosphorylation
S311 Phosphorylation
S312 Phosphorylation
S315 Phosphorylation
S322 Phosphorylation
T357 Phosphorylation
S362 Phosphorylation
S377 Phosphorylation
S380 Phosphorylation
S391 Phosphorylation
S393 Phosphorylation
S440 Phosphorylation
S443 Phosphorylation
T444 Phosphorylation
S452 Phosphorylation
T453 Phosphorylation
S464 Phosphorylation
S471 Phosphorylation
S474 Phosphorylation
S476 Phosphorylation
K479 Ubiquitination
K483 Ubiquitination
Y486 Phosphorylation
S488 Phosphorylation
S490 Phosphorylation
S507 Phosphorylation
S522 Phosphorylation
S528 Phosphorylation
T534 Phosphorylation
T540 Phosphorylation
S541 Phosphorylation
T544 Phosphorylation
K556 Acetylation
K566 Acetylation
K570 Acetylation
T572 Phosphorylation
S579 Phosphorylation
S587 Phosphorylation
S594 Phosphorylation
S600 Phosphorylation
S604 Phosphorylation
T627 Phosphorylation
S635 Phosphorylation
T647 Phosphorylation
S648 Phosphorylation
S652 Phosphorylation
S654 Phosphorylation
S672 Phosphorylation
S679 Phosphorylation
S680 Phosphorylation
S681 Phosphorylation
S683 Phosphorylation
T685 Phosphorylation
R688 Methylation
R692 Methylation
S697 Phosphorylation
K706 Methylation
S723 Phosphorylation
T727 Phosphorylation
T734 Phosphorylation
K744 Acetylation
S750 Phosphorylation
S754 Phosphorylation
K756 Ubiquitination
S757 Phosphorylation
S760 Phosphorylation
S763 Phosphorylation
T764 Phosphorylation
K766 Acetylation
S770 Phosphorylation
T773 Phosphorylation
T775 Phosphorylation
S791 Phosphorylation
S797 Phosphorylation
S806 Phosphorylation
S808 Phosphorylation
S884 Phosphorylation
S893 Phosphorylation
S927 Phosphorylation
T942 Phosphorylation
S954 Phosphorylation
S964 Phosphorylation
T966 Phosphorylation
S977 Phosphorylation
S981 Phosphorylation
S1000 Phosphorylation
T1002 Phosphorylation
T1005 Phosphorylation
T1006 Phosphorylation
S1012 Phosphorylation
S1014 Phosphorylation
T1017 Phosphorylation
S1035 Phosphorylation
S1046 Phosphorylation
S1048 Phosphorylation
T1053 Phosphorylation
S1154 Phosphorylation
T1170 Phosphorylation
S1181 Phosphorylation
S1182 Phosphorylation
S1212 Phosphorylation
S1219 Phosphorylation
S1220 Phosphorylation
S1226 Phosphorylation
S1233 Phosphorylation
S1236 Phosphorylation
S1238 Phosphorylation
T1245 Phosphorylation
S1248 Phosphorylation
S1252 Phosphorylation
S1253 Phosphorylation
S1260 Phosphorylation
T1263 Phosphorylation
S1265 Phosphorylation
S1267 Phosphorylation
T1281 Phosphorylation
T1291 Phosphorylation
K1317 Methylation
K1320 Methylation
S1366 Phosphorylation
S1369 Phosphorylation
T1370 Phosphorylation
S1381 Phosphorylation
S1382 Phosphorylation
S1386 Phosphorylation
S1405 Phosphorylation
K1709 Ubiquitination
T1818 Phosphorylation
S1823 Phosphorylation
S1826 Phosphorylation
T1832 Phosphorylation
S1836 Phosphorylation
T1837 Phosphorylation
S1840 Phosphorylation
S1843 Phosphorylation
Y1859 Phosphorylation
S1862 Phosphorylation
T1867 Phosphorylation
T1876 Phosphorylation

Research Backgrounds

Function:

May be involved in neuronal migration.

Subcellular Location:

Cytoplasm>Cytoskeleton.
Note: Associates with a subset of microtubule plus ends. Enriched in neuronal growth cones (By similarity).

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Broadly expressed at low levels. Expressed at high levels in heart, skeletal muscle and placenta.

Subunit Structure:

Interacts with tubulin.

Family&Domains:

Belongs to the Nav/unc-53 family.

Restrictive clause

 

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