MOT2 Antibody | Affinity Biosciences

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Western blot analysis of extracts from COS-7, using MOT2 Antibody.

Product:	MOT2 Antibody
Catalog:	DF9633
Description:	Rabbit polyclonal antibody to MOT2
Application:	WB
Reactivity:	Human, Mouse, Rat, Monkey
Mol.Wt.:	52 kDa; 52kD(Calculated).
Uniprot:	O60669
RRID:	AB_2842829

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Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific.

Size	Price	Inventory
100ul	$280	In stock
200ul	$350	In stock

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Related Downloads

MS Report

HPLC Report

MSDS

Data Sheet

COA

Protocols

WB Handbook

IHC Protocol

IF/ICC Protocol

Product Info

Source:

Rabbit

Application:

WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:

Human,Mouse,Rat,Monkey

Clonality:

Polyclonal

Specificity:

MOT2 Antibody detects endogenous levels of total MOT2.

RRID:

AB_2842829
Cite Format: Affinity Biosciences Cat# DF9633, RRID:AB_2842829.

Conjugate:

Unconjugated.

Purification:

The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Storage:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.

Alias:

Fold/Unfold

MCT 2; MCT; Monocarboxylate transporter 2; MonocarboxylateTransporter 2; MOT2; MOT2_HUMAN; SLC16A7; Solute carrier family 16 (monocarboxylate transporter), member 7; Solute carrier family 16 member 7; Solute carrier Family 16 Monocarboxylic Acid Transporters Member 7; Solute carrier family 16, member 7 (monocarboxylic acid transporter 2);

Immunogens

Immunogen:

Uniprot:

O60669(MOT2_HUMAN) >>Visit HPA database.

Gene(ID):

SLC16A7(9194)

Expression:

O60669 MOT2_HUMAN:

Detected in heart and in blood lymphocytes and monocytes (at protein level). High expression in testis, moderate to low in spleen, heart, kidney, pancreas, skeletal muscle, brain and Leukocyte. Restricted expression in normal tissues, but widely expressed in cancer cells.

Sequence:

O60669 MOT2_HUMAN:
Protein BLAST With
NCBI/
ExPASy/
Uniprot

MPPMPSAPPVHPPPDGGWGWIVVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYSEIAWISSIMLAVMYAGGPVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFITGLGLAFNLQPALTIIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLILGSLLLNACVAGSLMRPLGPNQTTSKSKNKTGKTEDDSSPKKIKTKKSTWEKVNKYLDFSLFKHRGFLIYLSGNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAFLLSVMAFVDMFARPSVGLIANSKYIRPRIQYFFSFAIMFNGVCHLLCPLAQDYTSLVLYAVFFGLGFGSVSSVLFETLMDLVGAPRFSSAVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYMYMSCGAIVVAASVWLLIGNAINYRLLAKERKEENARQKTRESEPLSKSKHSEDVNVKVSNAQSVTSERETNI

PTMs - O60669 As Substrate

O60669

Site	PTM Type	Source
S33	Phosphorylation	Uniprot
Y34	Phosphorylation	Uniprot
S62	Phosphorylation	Uniprot
S218	Phosphorylation	Uniprot
K221	Ubiquitination	Uniprot
K232	Ubiquitination	Uniprot
K444	Ubiquitination	Uniprot
T445	Phosphorylation	Uniprot
S448	Phosphorylation	Uniprot
K453	Ubiquitination	Uniprot
K455	Ubiquitination	Uniprot
S457	Phosphorylation	Uniprot
K463	Ubiquitination	Uniprot
S465	Phosphorylation	Uniprot
S469	Phosphorylation	Uniprot
S472	Phosphorylation	Uniprot

Research Backgrounds

O60669_MOT2_HUMAN

Function:

Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Functions as high-affinity pyruvate transporter.

Subcellular Location:

Cell membrane>Multi-pass membrane protein.

Tissue Specificity:

Subunit Structure:

Interacts with GRID2IP.

Family&Domains:

Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.

Restrictive clause

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For Research Use Only.
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MOT2 Antibody - #DF9633