Product: IMMP2L Antibody
Catalog: DF9630
Description: Rabbit polyclonal antibody to IMMP2L
Application: WB IHC IF/ICC
Reactivity: Human, Mouse, Rat
Prediction: Zebrafish, Bovine, Horse, Xenopus
Mol.Wt.: 20 kDa; 20kD(Calculated).
Uniprot: Q96T52
RRID: AB_2842826

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 100ul $280 In stock
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Product Info

Source:
Rabbit
Application:
WB 1:1000-3000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Zebrafish(91%), Bovine(100%), Horse(100%), Xenopus(100%)
Clonality:
Polyclonal
Specificity:
IMMP2L Antibody detects endogenous levels of total IMMP2L.
RRID:
AB_2842826
Cite Format: Affinity Biosciences Cat# DF9630, RRID:AB_2842826.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

EC 3.4.21; IMP2; IMP2 inner mitochondrial membrane peptidase like (S. cerevisiae); IMP2 inner mitochondrial membrane protease like (S. cerevisiae); IMP2 inner mitochondrial membrane protease like; IMP2 like; IMP2 like protein; IMP2-LIKE; Inner mitochondrial membrane peptidase 2 like; Mitochondrial inner membrane protease subunit 2; OTTHUMP00000207168; OTTHUMP00000207189;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
Q96T52 IMP2L_HUMAN:

Expressed in all tissues tested except adult liver and lung.

Sequence:
MAQSQGWVKRYIKAFCKGFFVAVPVAVTFLDRVACVARVEGASMQPSLNPGGSQSSDVVLLNHWKVRNFEVHRGDIVSLVSPKNPEQKIIKRVIALEGDIVRTIGHKNRYVKVPRGHIWVEGDHHGHSFDSNSFGPVSLGLLHAHATHILWPPERWQKLESVLPPERLPVQREEE

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Horse
100
Bovine
100
Xenopus
100
Zebrafish
91
Pig
0
Sheep
0
Dog
0
Chicken
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q96T52 As Substrate

Site PTM Type Enzyme
S43 Phosphorylation
S47 Phosphorylation
K83 Ubiquitination
K88 Ubiquitination
K112 Methylation

Research Backgrounds

Function:

Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO.

Subcellular Location:

Mitochondrion inner membrane>Single-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Expressed in all tissues tested except adult liver and lung.

Subunit Structure:

Heterodimer of 2 subunits, IMMPL1 and IMMPL2.

Family&Domains:

Belongs to the peptidase S26 family. IMP2 subfamily.

Research Fields

· Genetic Information Processing > Folding, sorting and degradation > Protein export.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.