NKX62 Antibody - #DF9590
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Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF9590, RRID:AB_2842786.
Fold/Unfold
GTX; Homeobox protein NK-6 homolog B; Homeobox protein Nkx 6.2; Homeobox protein Nkx-6.2; MGC126684; NK6 homeobox 2; NK6 transcription factor related, locus 2; NKX6-2; NKX6.2; NKX62_HUMAN; NKX6B;
Immunogens
- Q9C056 NKX62_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MDTNRPGAFVLSSAPLAALHNMAEMKTSLFPYALQGPAGFKAPALGGLGAQLPLGTPHGISDILGRPVGAAGGGLLGGLPRLNGLASSAGVYFGPAAAVARGYPKPLAELPGRPPIFWPGVVQGAPWRDPRLAGPAPAGGVLDKDGKKKHSRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKRHAVEMASAKKKQDSDAEKLKVGGSDAEDDDEYNRPLDPNSDDEKITRLLKKHKPSNLALVSPCGGGAGDAL
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9C056 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K215 | Acetylation | Uniprot |
Research Backgrounds
Transcription factor with repressor activity involved in the regulation of axon-glial interactions at myelin paranodes in oligodendrocytes. Binds to the consensus DNA sequence 5'-(A/T)TTAATGA-3'. In oligodendrocytes, binds to MBP and PLP1 promoter regions.
Nucleus.
Highest expression in brain.
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