HOXC11 Antibody | Affinity Biosciences

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Western blot analysis of HOXC11 using MCF7 whole cell lysates.

Product:	HOXC11 Antibody
Catalog:	DF9580
Description:	Rabbit polyclonal antibody to HOXC11
Application:	WB
Reactivity:	Human, Mouse, Rat
Prediction:	Pig, Bovine, Horse, Rabbit, Dog
Mol.Wt.:	34 kDa; 34kD(Calculated).
Uniprot:	O43248
RRID:	AB_2842776

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Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific.

Size	Price	Inventory
100ul	$280	In stock
200ul	$350	In stock

Lead Time: Same day delivery

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Related Downloads

MS Report

HPLC Report

MSDS

Data Sheet

COA

Protocols

WB Handbook

IHC Protocol

IF/ICC Protocol

Product Info

Source:

Rabbit

Application:

WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:

Human,Mouse,Rat

Prediction:

Pig(91%), Bovine(91%), Horse(91%), Rabbit(100%), Dog(91%)

Clonality:

Polyclonal

Specificity:

HOXC11 Antibody detects endogenous levels of total HOXC11.

RRID:

AB_2842776
Cite Format: Affinity Biosciences Cat# DF9580, RRID:AB_2842776.

Conjugate:

Unconjugated.

Purification:

The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Storage:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.

Alias:

Fold/Unfold

Homeo box C11; Homeobox C11; Homeobox protein Hox C11; Homeobox protein Hox-3H; Homeobox protein Hox-C11; HOX3H; HOXC11; HXC11_HUMAN; MGC4906;

Immunogens

Immunogen:

Uniprot:

O43248(HXC11_HUMAN) >>Visit HPA database.

Gene(ID):

HOXC11(3227)

Sequence:

O43248 HXC11_HUMAN:
Protein BLAST With
NCBI/
ExPASy/
Uniprot

MFNSVNLGNFCSPSRKERGADFGERGSCASNLYLPSCTYYMPEFSTVSSFLPQAPSRQISYPYSAQVPPVREVSYGLEPSGKWHHRNSYSSCYAAADELMHRECLPPSTVTEILMKNEGSYGGHHHPSAPHATPAGFYSSVNKNSVLPQAFDRFFDNAYCGGGDPPAEPPCSGKGEAKGEPEAPPASGLASRAEAGAEAEAEEENTNPSSSGSAHSVAKEPAKGAAPNAPRTRKKRCPYSKFQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKLSRDRLQYFSGNPLL

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species

Results

Score

Rabbit

100

Pig

Horse

Bovine

Dog

Sheep

Xenopus

Zebrafish

Chicken

Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - O43248 As Substrate

O43248

Site	PTM Type	Source
S12	Phosphorylation	Uniprot
S60	Phosphorylation	Uniprot
S88	Phosphorylation	Uniprot
K143	Ubiquitination	Uniprot
K178	Sumoylation	Uniprot
K178	Ubiquitination	Uniprot
T206	Phosphorylation	Uniprot
K223	Ubiquitination	Uniprot

Research Backgrounds

O43248_HXC11_HUMAN

Function:

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Binds to a promoter element of the lactase-phlorizin hydrolase gene.

Subcellular Location:

Nucleus.

Family&Domains:

Belongs to the Abd-B homeobox family.

References

1). HOXC11 Expression Is Associated with the Progression of Colon Adenocarcinoma and Is a Prognostic Biomarker. DNA and Cell Biology, 2021 (PubMed: 34415792) [IF=3.1]

Restrictive clause

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.

HOXC11 Antibody - #DF9580