HEATR1 Antibody - #DF9569

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Product: HEATR1 Antibody
Catalog: DF9569
Description: Rabbit polyclonal antibody to HEATR1
Application: WB IHC
Reactivity: Human, Mouse, Rat
Prediction: Pig, Horse, Sheep, Rabbit, Dog
Mol.Wt.: 242kDa; 242kD(Calculated).
Uniprot: Q9H583
RRID: AB_2842765

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 100ul $280 In stock
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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:1000-3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Pig(100%), Horse(100%), Sheep(90%), Rabbit(80%), Dog(90%)
Clonality:
Polyclonal
Specificity:
HEATR1 Antibody detects endogenous levels of total HEATR1.
RRID:
AB_2842765
Cite Format: Affinity Biosciences Cat# DF9569, RRID:AB_2842765.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

BAP28; HEAT repeat containing 1; HEAT repeat containing protein 1; Protein BAP28; RP11-385F5.3; UTP10; UTP10 small subunit (SSU) processome component homolog;

Immunogens

Immunogen:
Uniprot:

Q9H583(HEAT1_HUMAN) >>Visit HPA database.

Gene(ID):
HEATR1(55127)
Sequence:
MTSLAQQLQRLALPQSDASLLSRDEVASLLFDPKEAATIDRDTAFAIGCTGLEELLGIDPSFEQFEAPLFSQLAKTLERSVQTKAVNKQLDENISLFLIHLSPYFLLKPAQKCLEWLIHRFHIHLYNQDSLIACVLPYHETRIFVRVIQLLKINNSKHRWFWLLPVKQSGVPLAKGTLITHCYKDLGFMDFICSLVTKSVKVFAEYPGSSAQLRVLLAFYASTIVSALVAAEDVSDNIIAKLFPYIQKGLKSSLPDYRAATYMIICQISVKVTMENTFVNSLASQIIKTLTKIPSLIKDGLSCLIVLLQRQKPESLGKKPFPHLCNVPDLITILHGISETYDVSPLLHYMLPHLVVSIIHHVTGEETEGMDGQIYKRHLEAILTKISLKNNLDHLLASLLFEEYISYSSQEEMDSNKVSLLNEQFLPLIRLLESKYPRTLDVVLEEHLKEIADLKKQELFHQFVSLSTSGGKYQFLADSDTSLMLSLNHPLAPVRILAMNHLKKIMKTSKEGVDESFIKEAVLARLGDDNIDVVLSAISAFEIFKEHFSSEVTISNLLNLFQRAELSKNGEWYEVLKIAADILIKEEILSENDQLSNQVVVCLLPFMVINNDDTESAEMKIAIYLSKSGICSLHPLLRGWEEALENVIKSTKPGKLIGVANQKMIELLADNINLGDPSSMLKMVEDLISVGEEESFNLKQKVTFHVILSVLVSCCSSLKETHFPFAIRVFSLLQKKIKKLESVITAVEIPSEWHIELMLDRGIPVELWAHYVEELNSTQRVAVEDSVFLVFSLKKFIYALKAPKSFPKGDIWWNPEQLKEDSRDYLHLLIGLFEMMLNGADAVHFRVLMKLFIKVHLEDVFQLFKFCSVLWTYGSSLSNPLNCSVKTVLQTQALYVGCAMLSSQKTQCKHQLASISSPVVTSLLINLGSPVKEVRRAAIQCLQALSGVASPFYLIIDHLISKAEEITSDAAYVIQDLATLFEELQREKKLKSHQKLSETLKNLLSCVYSCPSYIAKDLMKVLQGVNGEMVLSQLLPMAEQLLEKIQKEPTAVLKDEAMVLHLTLGKYNEFSVSLLNEDPKSLDIFIKAVHTTKELYAGMPTIQITALEKITKPFFAAISDEKVQQKLLRMLFDLLVNCKNSHCAQTVSSVFKGISVNAEQVRIELEPPDKAKPLGTVQQKRRQKMQQKKSQDLESVQEVGGSYWQRVTLILELLQHKKKLRSPQILVPTLFNLLSRCLEPLPQEQGNMEYTKQLILSCLLNICQKLSPDGGKIPKDILDEEKFNVELIVQCIRLSEMPQTHHHALLLLGTVAGIFPDKVLHNIMSIFTFMGANVMRLDDTYSFQVINKTVKMVIPALIQSDSGDSIEVSRNVEEIVVKIISVFVDALPHVPEHRRLPILVQLVDTLGAEKFLWILLILLFEQYVTKTVLAAAYGEKDAILEADTEFWFSVCCEFSVQHQIQSLMNILQYLLKLPEEKEETIPKAVSFNKSESQEEMLQVFNVETHTSKQLRHFKFLSVSFMSQLLSSNNFLKKVVESGGPEILKGLEERLLETVLGYISAVAQSMERNADKLTVKFWRALLSKAYDLLDKVNALLPTETFIPVIRGLVGNPLPSVRRKALDLLNNKLQQNISWKKTIVTRFLKLVPDLLAIVQRKKKEGEEEQAINRQTALYTLKLLCKNFGAENPDPFVPVLNTAVKLIAPERKEEKNVLGSALLCIAEVTSTLEALAIPQLPSLMPSLLTTMKNTSELVSSEVYLLSALAALQKVVETLPHFISPYLEGILSQVIHLEKITSEMGSASQANIRLTSLKKTLATTLAPRVLLPAIKKTYKQIEKNWKNHMGPFMSILQEHIGVMKKEELTSHQSQLTAFFLEALDFRAQHSENDLEEVGKTENCIIDCLVAMVVKLSEVTFRPLFFKLFDWAKTEDAPKDRLLTFYNLADCIAEKLKGLFTLFAGHLVKPFADTLNQVNISKTDEAFFDSENDPEKCCLLLQFILNCLYKIFLFDTQHFISKERAEALMMPLVDQLENRLGGEEKFQERVTKHLIPCIAQFSVAMADDSLWKPLNYQILLKTRDSSPKVRFAALITVLALAEKLKENYIVLLPESIPFLAELMEDECEEVEHQCQKTIQQLETVLGEPLQSYF

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Sheep
90
Dog
90
Rabbit
80
Bovine
0
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9H583 As Substrate

Site PTM Type Enzyme
M1 Acetylation
T2 Acetylation
T2 Phosphorylation
R10 Methylation
S16 Phosphorylation
S19 Phosphorylation
K34 Ubiquitination
K84 Ubiquitination
K175 Ubiquitination
K248 Ubiquitination
K292 Ubiquitination
T363 Phosphorylation
T367 Phosphorylation
Y375 Phosphorylation
K435 Ubiquitination
K503 Ubiquitination
K510 Ubiquitination
S516 Phosphorylation
K519 Ubiquitination
S539 Phosphorylation
K568 Ubiquitination
K627 Ubiquitination
K655 Ubiquitination
K663 Ubiquitination
S709 Phosphorylation
K801 Ubiquitination
K808 Ubiquitination
K909 Ubiquitination
S917 Phosphorylation
S929 Phosphorylation
K995 Ubiquitination
K1047 Ubiquitination
K1054 Ubiquitination
Y1067 Phosphorylation
K1093 Ubiquitination
T1105 Phosphorylation
K1112 Ubiquitination
S1119 Phosphorylation
K1122 Ubiquitination
K1152 Ubiquitination
K1170 Ubiquitination
K1172 Ubiquitination
K1180 Ubiquitination
K1189 Ubiquitination
S1190 Phosphorylation
S1195 Phosphorylation
K1272 Ubiquitination
K1275 Ubiquitination
T1340 Phosphorylation
Y1341 Phosphorylation
S1360 Phosphorylation
K1477 Ubiquitination
K1483 Ubiquitination
S1486 Phosphorylation
K1489 Ubiquitination
S1490 Phosphorylation
S1492 Phosphorylation
K1508 Ubiquitination
S1517 Phosphorylation
S1519 Phosphorylation
S1526 Phosphorylation
S1527 Phosphorylation
K1533 Ubiquitination
S1537 Phosphorylation
K1575 Ubiquitination
T1597 Phosphorylation
T1599 Phosphorylation
S1614 Phosphorylation
K1618 Ubiquitination
K1626 Ubiquitination
K1634 Ubiquitination
K1655 Acetylation
K1675 Ubiquitination
K1679 Acetylation
K1679 Ubiquitination
S1794 Phosphorylation
K1811 Ubiquitination
T1815 Phosphorylation
T1816 Phosphorylation
R1820 Methylation
K1831 Acetylation
K1831 Ubiquitination
K1835 Ubiquitination
S1882 Phosphorylation
K1924 Ubiquitination
S1981 Phosphorylation
T2007 Phosphorylation
S2012 Phosphorylation
K2036 Ubiquitination
S2076 Phosphorylation
T2087 Phosphorylation

Research Backgrounds

Function:

Ribosome biogenesis factor. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I.

Subcellular Location:

Nucleus>Nucleolus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Subunit Structure:

May be a component of the proposed t-UTP subcomplex of the ribosomal small subunit (SSU) processome containing at least UTP4, WDR43, HEATR1, UTP15, WDR75.

Family&Domains:

Belongs to the HEATR1/UTP10 family.

Research Fields

· Genetic Information Processing > Translation > Ribosome biogenesis in eukaryotes.

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