GTPBP1 Antibody - #DF9549

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Product: GTPBP1 Antibody
Catalog: DF9549
Description: Rabbit polyclonal antibody to GTPBP1
Application: WB IHC
Reactivity: Human, Mouse, Rat
Prediction: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
Mol.Wt.: 72 kDa; 72kD(Calculated).
Uniprot: O00178
RRID: AB_2842745

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 100ul $280 In stock
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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:1000-3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Pig(100%), Zebrafish(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%), Chicken(100%), Xenopus(100%)
Clonality:
Polyclonal
Specificity:
GTPBP1 Antibody detects endogenous levels of total GTPBP1.
RRID:
AB_2842745
Cite Format: Affinity Biosciences Cat# DF9549, RRID:AB_2842745.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

G protein 1; G-protein 1; GP 1; GP-1; GP1; GTP binding protein 1; GTP-binding protein 1; GTPB1_HUMAN; GTPBP1;

Immunogens

Immunogen:
Uniprot:

O00178(GTPB1_HUMAN) >>Visit HPA database.

Gene(ID):
GTPBP1(9567)
Sequence:
MATERSRSAMDSPVPASMFAPEPSSPGAARAAAAAARLHGGFDSDCSEDGEALNGEPELDLTSKLVLVSPTSEQYDSLLRQMWERMDEGCGETIYVIGQGSDGTEYGLSEADMEASYATVKSMAEQIEADVILLRERQEAGGRVRDYLVRKRVGDNDFLEVRVAVVGNVDAGKSTLLGVLTHGELDNGRGFARQKLFRHKHEIESGRTSSVGNDILGFDSEGNVVNKPDSHGGSLEWTKICEKSTKVITFIDLAGHEKYLKTTVFGMTGHLPDFCMLMVGSNAGIVGMTKEHLGLALALNVPVFVVVTKIDMCPANILQETLKLLQRLLKSPGCRKIPVLVQSKDDVIVTASNFSSERMCPIFQISNVTGENLDLLKMFLNLLSPRTSYREEEPAEFQIDDTYSVPGVGTVVSGTTLRGLIKLNDTLLLGPDPLGNFLSIAVKSIHRKRMPVKEVRGGQTASFALKKIKRSSIRKGMVMVSPRLNPQASWEFEAEILVLHHPTTISPRYQAMVHCGSIRQTATILSMDKDCLRTGDKATVHFRFIKTPEYLHIDQRLVFREGRTKAVGTITKLLQTTNNSPMNSKPQQIKMQSTKKGPLTKRDEGGPSGGPAVGAPPPGDEASSVGAGQPAASSNLQPQPKPSSGGRRRGGQRHKVKSQGACVTPASGC

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Xenopus
100
Zebrafish
100
Chicken
100
Rabbit
100
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - O00178 As Substrate

Site PTM Type Enzyme
S6 Phosphorylation
S8 Phosphorylation
S12 Phosphorylation
S17 Phosphorylation
S24 Phosphorylation
S25 Phosphorylation
S44 Phosphorylation
S47 Phosphorylation
S69 Phosphorylation
S174 Phosphorylation
T175 Phosphorylation
T181 Phosphorylation
S205 Phosphorylation
K227 Ubiquitination
K239 Ubiquitination
K258 Acetylation
Y259 Phosphorylation
T263 Phosphorylation
S384 Phosphorylation
R456 Methylation
T460 Phosphorylation
S462 Phosphorylation
K466 Acetylation
S481 Phosphorylation
S517 Phosphorylation
T523 Phosphorylation
R556 Methylation
K565 Ubiquitination
T569 Phosphorylation
T576 Phosphorylation
T577 Phosphorylation
S580 Phosphorylation
S584 Phosphorylation
K585 Ubiquitination
K590 Ubiquitination
S658 Phosphorylation
C662 S-Nitrosylation
T664 Phosphorylation
C669 S-Nitrosylation

Research Backgrounds

Function:

Promotes degradation of target mRNA species. Plays a role in the regulation of circadian mRNA stability. Binds GTP and has GTPase activity (By similarity).

Subcellular Location:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Subunit Structure:

Interacts with EXOSC2/RRP4, EXOSC3/RRP40, EXOSC5/RRP46, HNRNPD, HNRNPR and SYNCRIP. Identified in a complex with AANAT mRNA, but does not bind mRNA by itself (By similarity).

Family&Domains:

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. GTPBP1 subfamily.

Restrictive clause

 

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For Research Use Only.
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