GINS2 Antibody - #DF9451
| Product: | GINS2 Antibody |
| Catalog: | DF9451 |
| Description: | Rabbit polyclonal antibody to GINS2 |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Prediction: | Pig, Zebrafish, Bovine, Horse, Sheep, Dog, Chicken, Xenopus |
| Mol.Wt.: | 21 kDa; 21kD(Calculated). |
| Uniprot: | Q9Y248 |
| RRID: | AB_2842647 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF9451, RRID:AB_2842647.
Fold/Unfold
DNA replication complex GINS protein PSF2; GINS complex subunit 2 (Psf2 homolog); GINS complex subunit 2; gins2; HSPC037; Pfs2; PSF2; PSF2_HUMAN;
Immunogens
- Q9Y248 PSF2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MDAAEVEFLAEKELVTIIPNFSLDKIYLIGGDLGPFNPGLPVEVPLWLAINLKQRQKCRLLPPEWMDVEKLEKMRDHERKEETFTPMPSPYYMELTKLLLNHASDNIPKADEIRTLVKDMWDTRIAKLRVSADSFVRQQEAHAKLDNLTLMEINTSGTFLTQALNHMYKLRTNLQPLESTQSQDF
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9Y248 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| M1 | Acetylation | Uniprot | |
| K70 | Ubiquitination | Uniprot | |
| K73 | Ubiquitination | Uniprot | |
| K80 | Ubiquitination | Uniprot | |
| S104 | Phosphorylation | Uniprot | |
| K109 | Ubiquitination | Uniprot | |
| K118 | Ubiquitination | Uniprot | |
| T158 | Phosphorylation | Uniprot | |
| S179 | Phosphorylation | Uniprot | |
| T180 | Phosphorylation | Uniprot | |
| S182 | Phosphorylation | Q13535 (ATR) | Uniprot |
Research Backgrounds
The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA.
Nucleus.
Component of the GINS complex which is a heterotetramer of GINS1, GINS2, GINS3 and GINS4. Forms a stable subcomplex with GINS3. GINS complex interacts with DNA primase in vitro.
Belongs to the GINS2/PSF2 family.
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For Research Use Only.
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