DSG3 Antibody - #DF9439
Product: | DSG3 Antibody |
Catalog: | DF9439 |
Description: | Rabbit polyclonal antibody to DSG3 |
Application: | WB IHC IF/ICC |
Reactivity: | Human, Rat |
Mol.Wt.: | 108kDa; 108kD(Calculated). |
Uniprot: | P32926 |
RRID: | AB_2842635 |
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Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF9439, RRID:AB_2842635.
Fold/Unfold
130 kD pemphigus vulgaris antigen; 130 kDa pemphigus vulgaris antigen; Balding; Cadherin family member 6; CDHF 6; CDHF6; Desmoglein 3; Desmoglein 3 precursor; Desmoglein-3; Desmoglein3; DKFZp686P23184; DSG 3; DSG3; DSG3_HUMAN; Pemphigus vulgaris antigen; PVA;
Immunogens
- P32926 DSG3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MMGLFPRTTGALAIFVVVILVHGELRIETKGQYDEEEMTMQQAKRRQKREWVKFAKPCREGEDNSKRNPIAKITSDYQATQKITYRISGVGIDQPPFGIFVVDKNTGDINITAIVDREETPSFLITCRALNAQGLDVEKPLILTVKILDINDNPPVFSQQIFMGEIEENSASNSLVMILNATDADEPNHLNSKIAFKIVSQEPAGTPMFLLSRNTGEVRTLTNSLDREQASSYRLVVSGADKDGEGLSTQCECNIKVKDVNDNFPMFRDSQYSARIEENILSSELLRFQVTDLDEEYTDNWLAVYFFTSGNEGNWFEIQTDPRTNEGILKVVKALDYEQLQSVKLSIAVKNKAEFHQSVISRYRVQSTPVTIQVINVREGIAFRPASKTFTVQKGISSKKLVDYILGTYQAIDEDTNKAASNVKYVMGRNDGGYLMIDSKTAEIKFVKNMNRDSTFIVNKTITAEVLAIDEYTGKTSTGTVYVRVPDFNDNCPTAVLEKDAVCSSSPSVVVSARTLNNRYTGPYTFALEDQPVKLPAVWSITTLNATSALLRAQEQIPPGVYHISLVLTDSQNNRCEMPRSLTLEVCQCDNRGICGTSYPTTSPGTRYGRPHSGRLGPAAIGLLLLGLLLLLLAPLLLLTCDCGAGSTGGVTGGFIPVPDGSEGTIHQWGIEGAHPEDKEITNICVPPVTANGADFMESSEVCTNTYARGTAVEGTSGMEMTTKLGAATESGGAAGFATGTVSGAASGFGAATGVGICSSGQSGTMRTRHSTGGTNKDYADGAISMNFLDSYFSQKAFACAEEDDGQEANDCLLIYDNEGADATGSPVGSVGCCSFIADDLDDSFLDSLGPKFKKLAEISLGVDGEGKEVQPPSKDSGYGIESCGHPIEVQQTGFVKCQTLSGSQGASALSTSGSVQPAVSIPDPLQHGNYLVTETYSASGSLVQPSTAGFDPLLTQNVIVTERVICPISSVPGNLAGPTQLRGSHTMLCTEDPCSRLI
PTMs - P32926 As Substrate
Site | PTM Type | Enzyme | Source |
---|---|---|---|
Y33 | Phosphorylation | Uniprot | |
S387 | Phosphorylation | Uniprot | |
T389 | Phosphorylation | Uniprot | |
T391 | Phosphorylation | Uniprot | |
N459 | N-Glycosylation | Uniprot | |
N545 | N-Glycosylation | Uniprot | |
T601 | O-Glycosylation | Uniprot | |
T602 | O-Glycosylation | Uniprot | |
Y608 | Phosphorylation | Uniprot | |
T723 | Phosphorylation | Uniprot | |
T768 | Phosphorylation | Uniprot | |
S771 | Phosphorylation | Uniprot | |
T772 | Phosphorylation | Uniprot | |
T775 | Phosphorylation | Uniprot | |
Y779 | Phosphorylation | Uniprot | |
S785 | Phosphorylation | Uniprot | |
S971 | Phosphorylation | Uniprot | |
S985 | Phosphorylation | Uniprot | |
T991 | Phosphorylation | Uniprot |
Research Backgrounds
Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
Cell membrane>Single-pass type I membrane protein. Cell junction>Desmosome.
Epidermis, tongue, tonsil, esophagus and carcinomas.
Three calcium ions are usually bound at the interface of each cadherin domain and rigidify the connections, imparting a strong curvature to the full-length ectodomain.
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