DHRS10 Antibody - #DF9435

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Product: DHRS10 Antibody
Catalog: DF9435
Description: Rabbit polyclonal antibody to DHRS10
Application: WB
Reactivity: Human, Mouse
Mol.Wt.: 28 kDa, 20 kDa; 28kD(Calculated).
Uniprot: Q9BPX1
RRID: AB_2842631

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Clonality:
Polyclonal
Specificity:
DHRS10 Antibody detects endogenous levels of total DHRS10.
RRID:
AB_2842631
Cite Format: Affinity Biosciences Cat# DF9435, RRID:AB_2842631.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

17 beta HSD 14; 17 beta hydroxysteroid dehydrogenase 14; 17 beta hydroxysteroid dehydrogenase DHRS10; Dehydrogenase/reductase (SDR family) member 10; Dehydrogenase/reductase SDR family member 10; DHRS10; Hydroxysteroid (17 beta) dehydrogenase 14; Retinal short chain dehydrogenase/reductase 3; Retinal short chain dehydrogenase/reductase retSDR3; retSDR3; SDR3; SDR47C1; Short chain dehydrogenase/reductase family 47C, member 1;

Immunogens

Immunogen:
Uniprot:

Q9BPX1(DHB14_HUMAN) >>Visit HPA database.

Gene(ID):
HSD17B14(51171)
Expression:
Q9BPX1 DHB14_HUMAN:

Highly expressed in brain, placenta, liver and kidney.

Sequence:
MATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASEANFCTGIELLVTGGAELGYGCKASRSTPVDAPDIPS

PTMs - Q9BPX1 As Substrate

Site PTM Type Enzyme
Y7 Phosphorylation
T15 Phosphorylation
T71 Phosphorylation

Research Backgrounds

Function:

Has NAD-dependent 17-beta-hydroxysteroid dehydrogenase activity. Converts oestradiol to oestrone. The physiological substrate is not known. Acts on oestradiol and 5-androstene-3-beta,17-beta-diol (in vitro).

Subcellular Location:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Highly expressed in brain, placenta, liver and kidney.

Subunit Structure:

Homotetramer.

Family&Domains:

Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Restrictive clause

 

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For Research Use Only.
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