Claudin 12 Antibody - #DF9390
| Product: | Claudin 12 Antibody |
| Catalog: | DF9390 |
| Description: | Rabbit polyclonal antibody to Claudin 12 |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| Mol.Wt.: | 27 kDa; 27kD(Calculated). |
| Uniprot: | P56749 |
| RRID: | AB_2842586 |
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF9390, RRID:AB_2842586.
Fold/Unfold
Claudin-12; Claudin12; CLD12_HUMAN; CLDN 12; CLDN12;
Immunogens
- P56749 CLD12_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGCRDVHAATVLSFLCGIASVAGLFAGTLLPNWRKLRLITFNRNEKNLTVYTGLWVKCARYDGSSDCLMYDTTWYSSVDQLDLRVLQFALPLSMLIAMGALLLCLIGMCNTAFRSSVPNIKLAKCLVNSAGCHLVAGLLFFLAGTVSLSPSIWVIFYNIHLNKKFEPVFSFDYAVYVTIASAGGLFMTSLILFIWYCTCKSLPSPFWQPLYSHPPSMHTYSQPYSARSRLSAIEIDIPVVSHTT
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P56749 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T111 | Phosphorylation | Uniprot | |
| S115 | Phosphorylation | Uniprot | |
| S116 | Phosphorylation | Uniprot | |
| K121 | Ubiquitination | Uniprot | |
| Y211 | Phosphorylation | Uniprot | |
| S216 | Phosphorylation | Uniprot | |
| Y220 | Phosphorylation | Uniprot | |
| S228 | Phosphorylation | Uniprot | |
| S231 | Phosphorylation | Uniprot |
Research Backgrounds
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
Cell junction>Tight junction. Cell membrane>Multi-pass membrane protein.
Interacts with OCLN.
Belongs to the claudin family.
Restrictive clause
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For Research Use Only.
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