LUC7L3 Antibody - #DF9386

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Product: LUC7L3 Antibody
Catalog: DF9386
Description: Rabbit polyclonal antibody to LUC7L3
Application: WB
Reactivity: Human, Mouse
Prediction: Pig, Bovine, Horse, Sheep, Dog, Chicken
Mol.Wt.: 51 kDa; 51kD(Calculated).
Uniprot: O95232
RRID: AB_2842582

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 100ul $280 In stock
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Related Downloads
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Prediction:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Dog(100%), Chicken(100%)
Clonality:
Polyclonal
Specificity:
LUC7L3 Antibody detects endogenous levels of total LUC7L3.
RRID:
AB_2842582
Cite Format: Affinity Biosciences Cat# DF9386, RRID:AB_2842582.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

cAMP regulatory element-associated protein 1; Cisplatin resistance-associated overexpressed protein; Cisplatin resistance-associated-overexpressed protein; CRE-associated protein 1; CREAP-1; CREAP1; CROP; LC7L3_HUMAN; Luc7-like protein 3; Luc7A; LUC7L3; O48; Okadaic acid-inducible phosphoprotein OA48-18;

Immunogens

Immunogen:
Uniprot:

O95232(LC7L3_HUMAN) >>Visit HPA database.

Gene(ID):
LUC7L3(51747)
Expression:
O95232 LC7L3_HUMAN:

Widely expressed. Highest levels in heart, brain, pancreas, thymus, ovary, small intestine and peripheral blood leukocytes, as well as cerebellum, putamen and pituitary gland. Lowest levels in lung, liver and kidney. Also expressed in fetal tissues, including brain, heart, kidney, thymus and lung.

Sequence:
MISAAQLLDELMGRDRNLAPDEKRSNVRWDHESVCKYYLCGFCPAELFTNTRSDLGPCEKIHDENLRKQYEKSSRFMKVGYERDFLRYLQSLLAEVERRIRRGHARLALSQNQQSSGAAGPTGKNEEKIQVLTDKIDVLLQQIEELGSEGKVEEAQGMMKLVEQLKEERELLRSTTSTIESFAAQEKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTSEDIKSEGDTQSN

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Chicken
100
Xenopus
0
Zebrafish
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - O95232 As Substrate

Site PTM Type Enzyme
M1 Acetylation
S3 Phosphorylation
K23 Ubiquitination
K36 Acetylation
Y38 Phosphorylation
R67 Methylation
K78 Acetylation
S110 Phosphorylation
S115 Phosphorylation
S116 Phosphorylation
K124 Ubiquitination
K135 Ubiquitination
S148 Phosphorylation
K160 Ubiquitination
K166 Acetylation
K166 Ubiquitination
K231 Acetylation
T238 Phosphorylation
S325 Phosphorylation
S327 Phosphorylation
S333 Phosphorylation
S335 Phosphorylation
S339 Phosphorylation
S345 Phosphorylation
S347 Phosphorylation
S367 Phosphorylation
S376 Phosphorylation
S389 Phosphorylation
S390 Phosphorylation
S393 Phosphorylation
T405 Phosphorylation
T419 Phosphorylation
S420 Phosphorylation
K424 Sumoylation
S425 Phosphorylation
T429 Phosphorylation
S431 Phosphorylation

Research Backgrounds

Function:

Binds cAMP regulatory element DNA sequence. May play a role in RNA splicing.

PTMs:

Phosphorylated in vitro by SRPK1, SRPK2 and CLK1.

Subcellular Location:

Nucleus speckle.
Note: The subnuclear localization is affected by cisplatin.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Widely expressed. Highest levels in heart, brain, pancreas, thymus, ovary, small intestine and peripheral blood leukocytes, as well as cerebellum, putamen and pituitary gland. Lowest levels in lung, liver and kidney. Also expressed in fetal tissues, including brain, heart, kidney, thymus and lung.

Subunit Structure:

May interact with SFRS1 and form homodimers. Interacts with JMJD6. Interacts with RBM25. Interacts with RSRC1 (via Arg/Ser-rich domain). Interacts with RRP1B.

Family&Domains:

Belongs to the Luc7 family.

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