CLCN1 Antibody - #DF9377
| Product: | CLCN1 Antibody |
| Catalog: | DF9377 |
| Description: | Rabbit polyclonal antibody to CLCN1 |
| Application: | WB |
| Reactivity: | Human |
| Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| Mol.Wt.: | 109kDa; 109kD(Calculated). |
| Uniprot: | P35523 |
| RRID: | AB_2842573 |
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF9377, RRID:AB_2842573.
Fold/Unfold
Chloride channel protein 1; Chloride channel protein; Chloride channel protein skeletal muscle; CIC 1; CIC1; ClC-1; CLC1; Clcn1; CLCN1_HUMAN; MGC138361; MGC142055; skeletal muscle;
Immunogens
- P35523 CLCN1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MEQSRSQQRGGEQSWWGSDPQYQYMPFEHCTSYGLPSENGGLQHRLRKDAGPRHNVHPTQIYGHHKEQFSDREQDIGMPKKTGSSSTVDSKDEDHYSKCQDCIHRLGQVVRRKLGEDGIFLVLLGLLMALVSWSMDYVSAKSLQAYKWSYAQMQPSLPLQFLVWVTFPLVLILFSALFCHLISPQAVGSGIPEMKTILRGVVLKEYLTMKAFVAKVVALTAGLGSGIPVGKEGPFVHIASICAAVLSKFMSVFCGVYEQPYYYSDILTVGCAVGVGCCFGTPLGGVLFSIEVTSTYFAVRNYWRGFFAATFSAFVFRVLAVWNKDAVTITALFRTNFRMDFPFDLKELPAFAAIGICCGLLGAVFVYLHRQVMLGVRKHKALSQFLAKHRLLYPGIVTFVIASFTFPPGMGQFMAGELMPREAISTLFDNNTWVKHAGDPESLGQSAVWIHPRVNVVIIIFLFFVMKFWMSIVATTMPIPCGGFMPVFVLGAAFGRLVGEIMAMLFPDGILFDDIIYKILPGGYAVIGAAALTGAVSHTVSTAVICFELTGQIAHILPMMVAVILANMVAQSLQPSLYDSIIQVKKLPYLPDLGWNQLSKYTIFVEDIMVRDVKFVSASYTYGELRTLLQTTTVKTLPLVDSKDSMILLGSVERSELQALLQRHLCPERRLRAAQEMARKLSELPYDGKARLAGEGLPGAPPGRPESFAFVDEDEDEDLSGKSELPPSLALHPSTTAPLSPEEPNGPLPGHKQQPEAPEPAGQRPSIFQSLLHCLLGRARPTKKKTTQDSTDLVDNMSPEEIEAWEQEQLSQPVCFDSCCIDQSPFQLVEQTTLHKTHTLFSLLGLHLAYVTSMGKLRGVLALEELQKAIEGHTKSGVQLRPPLASFRNTTSTRKSTGAPPSSAENWNLPEDRPGATGTGDVIAASPETPVPSPSPEPPLSLAPGKVEGELEELELVESPGLEEELADILQGPSLRSTDEEDEDELIL
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P35523 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K195 | Sumoylation | Uniprot | |
| T891 | Phosphorylation | Uniprot | |
| S892 | Phosphorylation | Uniprot | |
| T893 | Phosphorylation | Uniprot | |
| T917 | Phosphorylation | Uniprot | |
| T929 | Phosphorylation | Uniprot | |
| S977 | Phosphorylation | Uniprot | |
| T978 | Phosphorylation | Uniprot |
Research Backgrounds
Voltage-gated chloride channel. Plays an important role in membrane repolarization in skeletal muscle cells after muscle contraction.
Cell membrane>Multi-pass membrane protein.
Predominantly expressed in skeletal muscles.
Homodimer.
Belongs to the chloride channel (TC 2.A.49) family. ClC-1/CLCN1 subfamily.
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