Product: CEP41 Antibody
Catalog: DF9362
Description: Rabbit polyclonal antibody to CEP41
Application: WB IHC IF/ICC
Reactivity: Human, Mouse, Rat
Prediction: Pig, Bovine, Horse, Sheep, Rabbit, Dog
Mol.Wt.: 41 kDa; 41kD(Calculated).
Uniprot: Q9BYV8
RRID: AB_2842558

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 100ul $280 In stock
 200ul $350 In stock

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Product Info

Source:
Rabbit
Application:
IF/ICC 1:100-1:500, WB 1:1000-3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%)
Clonality:
Polyclonal
Specificity:
CEP41 Antibody detects endogenous levels of total CEP41.
RRID:
AB_2842558
Cite Format: Affinity Biosciences Cat# DF9362, RRID:AB_2842558.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

centrosomal protein 41 kDa; Centrosomal protein of 41 kDa; CEP 41; Cep41; CEP41_HUMAN; testis specific 14; testis specific gene A14; Testis specific gene A14 protein; testis specific protein A14; Testis-specific gene A14 protein;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
Q9BYV8 CEP41_HUMAN:

Isoform 1 and isoform 4 are expressed in testis and fetal tissues.

Sequence:
MSLRRHIGNPEYLMKRIPQNPRYQHIKSRLDTGNSMTKYTEKLEEIKKNYRYKKDELFKRLKVTTFAQLIIQVASLSDQTLEVTAEEIQRLEDNDSAASDPDAETTARTNGKGNPGEQSPSPEQFINNAGAGDSSRSTLQSVISGVGELDLDKGPVKKAEPHTKDKPYPDCPFLLLDVRDRDSYQQCHIVGAYSYPIATLSRTMNPYSNDILEYKNAHGKIIILYDDDERLASQAATTMCERGFENLFMLSGGLKVLAQKFPEGLITGSLPASCQQALPPGSARKRSSPKGPPLPAENKWRFTPEDLKKIEYYLEEEQGPADHPSRLNQANSSGRESKVPGARSAQNLPGGGPASHSNPRSLSSGHLQGKPWK

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Rabbit
100
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9BYV8 As Substrate

Site PTM Type Enzyme
Y12 Phosphorylation
S35 Phosphorylation
S96 Phosphorylation
S99 Phosphorylation
S119 Phosphorylation
S121 Phosphorylation
S282 Phosphorylation
S287 Phosphorylation
S288 Phosphorylation
Y312 Phosphorylation
S344 Phosphorylation
S363 Phosphorylation
K370 Acetylation

Research Backgrounds

Function:

Required during ciliogenesis for tubulin glutamylation in cilium. Probably acts by participating in the transport of TTLL6, a tubulin polyglutamylase, between the basal body and the cilium.

Subcellular Location:

Cytoplasm>Cytoskeleton>Microtubule organizing center>Centrosome. Cell projection>Cilium. Cytoplasm>Cytoskeleton>Cilium basal body.
Note: Localizes mainly to the cilium basal body and in primary cilia.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Isoform 1 and isoform 4 are expressed in testis and fetal tissues.

Subunit Structure:

Found in a complex with TTLL6.

Family&Domains:

Although it contains a rhodanese domain, does not display phosphatase activity, suggesting that the protein is enzymatically inactive.

Belongs to the CEP41 family.

Restrictive clause

 

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For Research Use Only.
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