CABP4 Antibody - #DF9308
| Product: | CABP4 Antibody |
| Catalog: | DF9308 |
| Description: | Rabbit polyclonal antibody to CABP4 |
| Application: | WB IF/ICC |
| Reactivity: | Human, Mouse |
| Prediction: | Pig, Bovine, Horse, Sheep, Dog |
| Mol.Wt.: | 30kDa; 30kD(Calculated). |
| Uniprot: | P57796 |
| RRID: | AB_2842504 |
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF9308, RRID:AB_2842504.
Fold/Unfold
CABP 4; CaBP4; CABP4_HUMAN; Calcium binding protein 4; Calcium-binding protein 4; CSNB 2B; CSNB2B;
Immunogens
- P57796 CABP4_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MTTEQARGQQGPNLAIGRQKPPAGVVTPKSDAEEPPLTRKRSKKERGLRGSRKRTGSSGEQTGPEAPGSSNNPPSTGEGPAGAPPASPGPASSRQSHRHRPDSLHDAAQRTYGPLLNRVFGKDRELGPEELDELQAAFEEFDTDRDGYISHRELGDCMRTLGYMPTEMELLEVSQHIKMRMGGRVDFEEFVELIGPKLREETAHMLGVRELRIAFREFDRDRDGRITVAELREAVPALLGEPLAGPELDEMLREVDLNGDGTVDFDEFVMMLSRH
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P57796 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K44 | Ubiquitination | Uniprot | |
| Y148 | Phosphorylation | Uniprot | |
| S150 | Phosphorylation | Uniprot | |
| Y163 | Phosphorylation | Uniprot |
Research Backgrounds
Involved in normal synaptic function through regulation of Ca(2+) influx and neurotransmitter release in photoreceptor synaptic terminals and in auditory transmission. Modulator of CACNA1D and CACNA1F, suppressing the calcium-dependent inactivation and shifting the activation range to more hyperpolarized voltages (By similarity).
Phosphorylated. Phosphorylation levels change with the light conditions and regulate the activity (By similarity).
Cytoplasm. Cell junction>Synapse>Presynapse.
Note: Found in rod spherules and cone pedicles of the presynapses from both types of photoreceptors.
Expressed in retina and in the inner hair cells (IHC) of the cochlea.
Interacts with CACNA1F and CACNA1D (via IQ domain) in a calcium independent manner. Interacts (via N-terminus) with UNC119.
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