Product: CAMLG Antibody
Catalog: DF9297
Description: Rabbit polyclonal antibody to CAMLG
Application: WB IHC
Reactivity: Human
Prediction: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
Mol.Wt.: 33 kDa; 33kD(Calculated).
Uniprot: P49069
RRID: AB_2842493

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 100ul $280 In stock
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Product Info

Source:
Rabbit
Application:
IHC 1:50-1:200, WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Prediction:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(88%), Dog(100%), Chicken(88%), Xenopus(86%)
Clonality:
Polyclonal
Specificity:
CAMLG Antibody detects endogenous levels of total CAMLG.
RRID:
AB_2842493
Cite Format: Affinity Biosciences Cat# DF9297, RRID:AB_2842493.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

calcium modulating cyclophilin ligand; calcium modulating ligand; Calcium signal modulating cyclophilin ligand; CAML; cyclophilin B binding protein; MGC163197;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
P49069 CAMLG_HUMAN:

Ubiquitous. Highest levels in brain, testis and ovary.

Sequence:
MESMAVATDGGERPGVPAGSGLSASQRRAELRRRKLLMNSEQRINRIMGFHRPGSGAEEESQTKSKQQDSDKLNSLSVPSVSKRVVLGDSVSTGTTDQQGGVAEVKGTQLGDKLDSFIKPPECSSDVNLELRQRNRGDLTADSVQRGSRHGLEQYLSRFEEAMKLRKQLISEKPSQEDGNTTEEFDSFRIFRLVGCALLALGVRAFVCKYLSIFAPFLTLQLAYMGLYKYFPKSEKKIKTTVLTAALLLSGIPAEVINRSMDTYSKMGEVFTDLCVYFFTFIFCHELLDYWGSEVP

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Chicken
88
Rabbit
88
Xenopus
86
Zebrafish
71
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - P49069 As Substrate

Site PTM Type Enzyme
T8 Phosphorylation
S23 Phosphorylation
S25 Phosphorylation
S40 Phosphorylation
S55 Phosphorylation
S61 Phosphorylation
K72 Acetylation
K83 Acetylation
S116 Phosphorylation
S143 Phosphorylation
R146 Methylation
S148 Phosphorylation
Y155 Phosphorylation
K164 Ubiquitination
K173 Ubiquitination
S175 Phosphorylation
S250 Phosphorylation

Research Backgrounds

Function:

Likely involved in the mobilization of calcium as a result of the TCR/CD3 complex interaction. Binds to cyclophilin B.

Subcellular Location:

Membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Ubiquitous. Highest levels in brain, testis and ovary.

Subunit Structure:

The N-terminal domain binds to TNFRSF13B/TACI.

(Microbial infection) Interacts with human herpes virus 8/HHV-8 protein K7; this interaction modulates intracellular calcium concentration.

Restrictive clause

 

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