Product: PRSS22 Antibody
Catalog: DF9287
Description: Rabbit polyclonal antibody to PRSS22
Application: WB IF/ICC
Reactivity: Human, Mouse
Mol.Wt.: 34 kDa; 34kD(Calculated).
Uniprot: Q9GZN4
RRID: AB_2842483

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 100ul $280 In stock
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Product Info

Source:
Rabbit
Application:
WB 1:1000-3000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Clonality:
Polyclonal
Specificity:
PRSS22 Antibody detects endogenous levels of total PRSS22.
RRID:
AB_2842483
Cite Format: Affinity Biosciences Cat# DF9287, RRID:AB_2842483.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Brain specific serine protease 4; BSSP 4; BSSP4; hBSSP 4; MGC9599; Prosemin; Protease serine 22; Protease serine S1 family member 22; PRSS 22; PRSS26; Serine protease 22; Serine protease 26; SP001LA; Tryptase epsilon;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
Q9GZN4 BSSP4_HUMAN:

Expressed abundantly in the epithelial cells of the airways, including trachea, esophagus and fetal lung. Scarce in adult lung. Expressed at low levels in placenta, pancreas, prostate and thyroid gland.

Sequence:
MVVSGAPPALGGGCLGTFTSLLLLASTAILNAARIPVPPACGKPQQLNRVVGGEDSTDSEWPWIVSIQKNGTHHCAGSLLTSRWVITAAHCFKDNLNKPYLFSVLLGAWQLGNPGSRSQKVGVAWVEPHPVYSWKEGACADIALVRLERSIQFSERVLPICLPDASIHLPPNTHCWISGWGSIQDGVPLPHPQTLQKLKVPIIDSEVCSHLYWRGAGQGPITEDMLCAGYLEGERDACLGDSGGPLMCQVDGAWLLAGIISWGEGCAERNRPGVYISLSAHRSWVEKIVQGVQLRGRAQGGGALRAPSQGSGAAARS

PTMs - Q9GZN4 As Substrate

Site PTM Type Enzyme
N70 N-Glycosylation

Research Backgrounds

Function:

Preferentially cleaves the synthetic substrate H-D-Leu-Thr-Arg-pNA compared to tosyl-Gly-Pro-Arg-pNA.

Subcellular Location:

Secreted.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Expressed abundantly in the epithelial cells of the airways, including trachea, esophagus and fetal lung. Scarce in adult lung. Expressed at low levels in placenta, pancreas, prostate and thyroid gland.

Family&Domains:

Belongs to the peptidase S1 family.

Restrictive clause

 

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