Product: BMP15 Antibody
Catalog: DF9281
Description: Rabbit polyclonal antibody to BMP15
Application: WB
Reactivity: Human, Mouse
Mol.Wt.: 45 kDa,55kDa; 45kD(Calculated).
Uniprot: O95972
RRID: AB_2842477

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 100ul $280 In stock
 200ul $350 In stock

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Product Info

Source:
Rabbit
Application:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Clonality:
Polyclonal
Specificity:
BMP15 Antibody detects endogenous levels of total BMP15.
RRID:
AB_2842477
Cite Format: Affinity Biosciences Cat# DF9281, RRID:AB_2842477.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

BMP 15; BMP-15; BMP15; BMP15_HUMAN; Bone morphogenetic protein 15; GDF 9B; GDF-9B; GDF9B; Growth/differentiation factor 9B; ODG2; POF4;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Sequence:
MVLLSILRILFLCELVLFMEHRAQMAEGGQSSIALLAEAPTLPLIEELLEESPGEQPRKPRLLGHSLRYMLELYRRSADSHGHPRENRTIGATMVRLVKPLTNVARPHRGTWHIQILGFPLRPNRGLYQLVRATVVYRHHLQLTRFNLSCHVEPWVQKNPTNHFPSSEGDSSKPSLMSNAWKEMDITQLVQQRFWNNKGHRILRLRFMCQQQKDSGGLELWHGTSSLDIAFLLLYFNDTHKSIRKAKFLPRGMEEFMERESLLRRTRQADGISAEVTASSSKHSGPENNQCSLHPFQISFRQLGWDHWIIAPPFYTPNYCKGTCLRVLRDGLNSPNHAIIQNLINQLVDQSVPRPSCVPYKYVPISVLMIEANGSILYKEYEGMIAESCTCR

PTMs - O95972 As Substrate

Site PTM Type Enzyme
S66 Phosphorylation
T89 Phosphorylation
T102 Phosphorylation
Y235 Phosphorylation
S273 Phosphorylation
T277 O-Glycosylation
S366 Phosphorylation
Y378 Phosphorylation

Research Backgrounds

Function:

May be involved in follicular development. Oocyte-specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth.

Subcellular Location:

Secreted.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Subunit Structure:

Homodimer. But, in contrast to other members of this family, cannot be disulfide-linked.

Family&Domains:

Belongs to the TGF-beta family.

Research Fields

· Organismal Systems > Endocrine system > Ovarian steroidogenesis.

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