TF3C3 Antibody - #DF8728

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Product: TF3C3 Antibody
Catalog: DF8728
Description: Rabbit polyclonal antibody to TF3C3
Application: WB IF/ICC
Reactivity: Human, Mouse, Monkey
Prediction: Pig, Bovine, Horse, Sheep, Rabbit, Dog
Mol.Wt.: 101 kDa; 101kD(Calculated).
Uniprot: Q9Y5Q9
RRID: AB_2841932

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 100ul $280 In stock
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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:1000-3000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Monkey
Prediction:
Pig(92%), Bovine(92%), Horse(86%), Sheep(92%), Rabbit(92%), Dog(83%)
Clonality:
Polyclonal
Specificity:
TF3C3 Antibody detects endogenous levels of total TF3C3.
RRID:
AB_2841932
Cite Format: Affinity Biosciences Cat# DF8728, RRID:AB_2841932.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

General transcription factor 3C polypeptide 3; general transcription factor IIIC, polypeptide 3 (102kD); general transcription factor IIIC, polypeptide 3, 102kD; GTF3C3; TF3C-gamma; TF3C3_HUMAN; TFIIIC 102 kDa subunit; TFIIIC gamma; TFIIIC102; TFIIIC2 102; TFIIICgamma; Transcription factor IIIC 102 kDa subunit; transcription factor IIIC gamma subunit; Transcription factor IIIC subunit gamma; transcription factor IIIC, 102 kD;

Immunogens

Immunogen:
Uniprot:

Q9Y5Q9(TF3C3_HUMAN) >>Visit HPA database.

Gene(ID):
GTF3C3(9330)
Sequence:
MSGFSPELIDYLEGKISFEEFERRREERKTREKKSLQEKGKLSAEENPDDSEVPSSSGINSTKSQDKDVNEGETSDGVRKSVHKVFASMLGENEDDEEEEEEEEEEEEEEETPEQPTAGDVFVLEMVLNRETKKMMKEKRPRSKLPRALRGLMGEANIRFARGEREEAILMCMEIIRQAPLAYEPFSTLAMIYEDQGDMEKSLQFELIAAHLNPSDTEEWVRLAEMSLEQDNIKQAIFCYTKALKYEPTNVRYLWERSSLYEQMGDHKMAMDGYRRILNLLSPSDGERFMQLARDMAKSYYEANDVTSAINIIDEAFSKHQGLVSMEDVNIAAELYISNKQYDKALEIITDFSGIVLEKKTSEEGTSEENKAPENVTCTIPDGVPIDITVKLMVCLVHLNILEPLNPLLTTLVEQNPEDMGDLYLDVAEAFLDVGEYNSALPLLSALVCSERYNLAVVWLRHAECLKALGYMERAAESYGKVVDLAPLHLDARISLSTLQQQLGQPEKALEALEPMYDPDTLAQDANAAQQELKLLLHRSTLLFSQGKMYGYVDTLLTMLAMLLKVAMNRAQVCLISSSKSGERHLYLIKVSRDKISDSNDQESANCDAKAIFAVLTSVLTKDDWWNLLLKAIYSLCDLSRFQEAELLVDSSLEYYSFYDDRQKRKELEYFGLSAAILDKNFRKAYNYIRIMVMENVNKPQLWNIFNQVTMHSQDVRHHRFCLRLMLKNPENHALCVLNGHNAFVSGSFKHALGQYVQAFRTHPDEPLYSFCIGLTFIHMASQKYVLRRHALIVQGFSFLNRYLSLRGPCQESFYNLGRGLHQLGLIHLAIHYYQKALELPPLVVEGIELDQLDLRRDIAYNLSLIYQSSGNTGMAQTLLYTYCSI

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
92
Bovine
92
Sheep
92
Rabbit
92
Horse
86
Dog
83
Chicken
67
Xenopus
0
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9Y5Q9 As Substrate

Site PTM Type Enzyme
S2 Acetylation
S5 Phosphorylation
K41 Ubiquitination
S43 Phosphorylation
S51 Phosphorylation
K63 Ubiquitination
K67 Ubiquitination
S75 Phosphorylation
K80 Ubiquitination
K137 Ubiquitination
R150 Methylation
S187 Phosphorylation
T188 Phosphorylation
K234 Sumoylation
K234 Ubiquitination
K242 Ubiquitination
K245 Ubiquitination
Y246 Phosphorylation
K268 Ubiquitination
R275 Methylation
S282 Phosphorylation
S284 Phosphorylation
K298 Ubiquitination
K344 Ubiquitination
K359 Ubiquitination
T366 Phosphorylation
T377 Phosphorylation
Y453 Phosphorylation
K467 Ubiquitination
Y471 Phosphorylation
K481 Ubiquitination
S495 Phosphorylation
S497 Phosphorylation
K508 Ubiquitination
K534 Ubiquitination
K580 Ubiquitination
K590 Ubiquitination
S592 Phosphorylation
K595 Ubiquitination
Y686 Phosphorylation
K699 Sumoylation
K728 Ubiquitination

Research Backgrounds

Function:

Involved in RNA polymerase III-mediated transcription. Integral, tightly associated component of the DNA-binding TFIIIC2 subcomplex that directly binds tRNA and virus-associated RNA promoters.

Subcellular Location:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Subunit Structure:

Part of the TFIIIC subcomplex TFIIIC2, consisting of six subunits, GTF3C1, GTF3C2, GTF3C3, GTF3C4, GTF3C5 and GTF3C6. Interacts with BRF1 and TBP.

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For Research Use Only.
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