ADCK1 Antibody - #AF0541
| Product: | ADCK1 Antibody |
| Catalog: | AF0541 |
| Description: | Rabbit polyclonal antibody to ADCK1 |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken |
| Mol.Wt.: | 61kDa; 61kD(Calculated). |
| Uniprot: | Q86TW2 |
| RRID: | AB_2834297 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# AF0541, RRID:AB_2834297.
Fold/Unfold
2610005A10Rik; aarF domain containing kinase 1; ADCK 1; ADCK1; ADCK1_HUMAN; BOS_11212; FLJ39600; MGC142877; Uncharacterized aarF domain containing protein kinase 1; Uncharacterized aarF domain-containing protein kinase 1;
Immunogens
- Q86TW2 ADCK1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MARKALKLASWTSMALAASGIYFYSNKYLDPNDFGAVRVGRAVATTAVISYDYLTSLKSVPYGSEEYLQLRSKSWPVFLQVHLRSARRLCELCCANRGTFIKVGQHLGALDYLLPEEYTSTLKVLHSQAPQSSMQEIRQVIREDLGKEIHDLFQSFDDTPLGTASLAQVHKAVLHDGRTVAVKVQHPKVRAQSSKDILLMEVLVLAVKQLFPEFEFMWLVDEAKKNLPLELDFLNEGRNAEKVSQMLRHFDFLKVPRIHWDLSTERVLLMEFVDGGQVNDRDYMERNKIDVNEISRHLGKMYSEMIFVNGFVHCDPHPGNVLVRKHPGTGKAEIVLLDHGLYQMLTEEFRLNYCHLWQSLIWTDMKRVKEYSQRLGAGDLYPLFACMLTARSWDSVNRGISQAPVTATEDLEIRNNAANYLPQISHLLNHVPRQMLLILKTNDLLRGIEAALGTRASASSFLNMSRCCIRALAEHKKKNTCSFFRRTQISFSEAFNLWQINLHELILRVKGLKLADRVLALICWLFPAPL
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q86TW2 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y67 | Phosphorylation | Uniprot | |
| Y112 | Phosphorylation | Uniprot | |
| K183 | Ubiquitination | Uniprot | |
| K225 | Ubiquitination | Uniprot | |
| T329 | Phosphorylation | Uniprot | |
| T441 | Phosphorylation | Uniprot |
Research Backgrounds
Appears to be essential for maintaining mitochondrial cristae formation and mitochondrial function by acting via YME1L1 in a kinase-independent manner to regulate essential mitochondrial structural proteins OPA1 and IMMT. The action of this enzyme is not yet clear (Probable). It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr) (Probable).
Secreted.
Belongs to the protein kinase superfamily. ADCK protein kinase family.
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