SFXN4 Antibody - #AF0580
(1)
| Product: | SFXN4 Antibody |
| Catalog: | AF0580 |
| Description: | Rabbit polyclonal antibody to SFXN4 |
| Application: | WB IF/ICC |
| Reactivity: | Human |
| Mol.Wt.: | 37kDa; 38kD(Calculated). |
| Uniprot: | Q6P4A7 |
| RRID: | AB_2834289 |
Related Downloads
Protocols
Product Info
Source:
Rabbit
Application:
WB 1:500-1:2000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Reactivity:
Human
Clonality:
Polyclonal
Specificity:
SFXN4 Antibody detects endogenous levels of total SFXN4.
RRID:
AB_2834289
Cite Format: Affinity Biosciences Cat# AF0580, RRID:AB_2834289.
Cite Format: Affinity Biosciences Cat# AF0580, RRID:AB_2834289.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:
Fold/Unfold
BCRM1; Breast cancer resistance marker 1; SFXN 4; Sideroflexin 4;
Immunogens
Immunogen:
Uniprot:
Gene(ID):
Description:
Sfxn4 Potential iron transporter. Belongs to the sideroflexin family. 3 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Sequence:
- Q6P4A7 SFXN4_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSLEQEEETQPGRLLGRRDAVPAFIEPNVRFWITERQSFIRRFLQWTELLDPTNVFISVESIENSRQLLCTNEDVSSPASADQRIQEAWKRSLATVHPDSSNLIPKLFRPAAFLPFMAPTVFLSMTPLKGIKSVILPQVFLCAYMAAFNSINGNRSYTCKPLERSLLMAGAVASSTFLGVIPQFVQMKYGLTGPWIKRLLPVIFLVQASGMNVYMSRSLESIKGIAVMDKEGNVLGHSRIAGTKAVRETLASRIVLFGTSALIPEVFTYFFKRTQYFRKNPGSLWILKLSCTVLAMGLMVPFSFSIFPQIGQIQYCSLEEKIQSPTEETEIFYHRGV
PTMs - Q6P4A7 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S2 | Acetylation | Uniprot | |
| S2 | Phosphorylation | Uniprot | |
| K90 | Ubiquitination | Uniprot | |
| K106 | Ubiquitination | Uniprot | |
| C159 | S-Nitrosylation | Uniprot | |
| K160 | Ubiquitination | Uniprot | |
| K197 | Acetylation | Uniprot | |
| K197 | Ubiquitination | Uniprot | |
| S209 | Phosphorylation | Uniprot | |
| K223 | Ubiquitination | Uniprot | |
| K230 | Ubiquitination | Uniprot | |
| S324 | Phosphorylation | Uniprot |
Research Backgrounds
Function:
Mitochondrial amino-acid transporter (By similarity). Does not act as a serine transporter: not able to mediate transport of serine into mitochondria.
Subcellular Location:
Mitochondrion inner membrane>Multi-pass membrane protein.
Family&Domains:
Belongs to the sideroflexin family.
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