TM16G Antibody - #AF0648
| Product: | TM16G Antibody |
| Catalog: | AF0648 |
| Description: | Rabbit polyclonal antibody to TM16G |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human |
| Prediction: | Horse, Dog |
| Mol.Wt.: | 105kDa; 106kD(Calculated). |
| Uniprot: | Q6IWH7 |
| RRID: | AB_2834287 |
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# AF0648, RRID:AB_2834287.
Fold/Unfold
Ano7; ANO7_HUMAN; Anoctamin 7; Anoctamin-7; D TMPP; D-TMPP; Dresden transmembrane protein of the prostate; DTMPP; IPCA 5; IPCA-5; IPCA5; New gene expressed in prostate; NGEP; PCANAP5; PCANAP5L; Prostate cancer associated protein 5; Prostate cancer-associated protein 5; TMEM16G; Transmembrane protein 16G;
Immunogens
- Q6IWH7 ANO7_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MRMAATAWAGLQGPPLPTLCPAVRTGLYCRDQAHAERWAMTSETSSGSHCARSRMLRRRAQEEDSTVLIDVSPPEAEKRGSYGSTAHASEPGGQQAAACRAGSPAKPRIADFVLVWEEDLKLDRQQDSAARDRTDMHRTWRETFLDNLRAAGLCVDQQDVQDGNTTVHYALLSASWAVLCYYAEDLRLKLPLQELPNQASNWSAGLLAWLGIPNVLLEVVPDVPPEYYSCRFRVNKLPRFLGSDNQDTFFTSTKRHQILFEILAKTPYGHEKKNLLGIHQLLAEGVLSAAFPLHDGPFKTPPEGPQAPRLNQRQVLFQHWARWGKWNKYQPLDHVRRYFGEKVALYFAWLGFYTGWLLPAAVVGTLVFLVGCFLVFSDIPTQELCGSKDSFEMCPLCLDCPFWLLSSACALAQAGRLFDHGGTVFFSLFMALWAVLLLEYWKRKSATLAYRWDCSDYEDTEERPRPQFAASAPMTAPNPITGEDEPYFPERSRARRMLAGSVVIVVMVAVVVMCLVSIILYRAIMAIVVSRSGNTLLAAWASRIASLTGSVVNLVFILILSKIYVSLAHVLTRWEMHRTQTKFEDAFTLKVFIFQFVNFYSSPVYIAFFKGRFVGYPGNYHTLFGVRNEECAAGGCLIELAQELLVIMVGKQVINNMQEVLIPKLKGWWQKFRLRSKKRKAGASAGASQGPWEDDYELVPCEGLFDEYLEMVLQFGFVTIFVAACPLAPLFALLNNWVEIRLDARKFVCEYRRPVAERAQDIGIWFHILAGLTHLAVISNAFLLAFSSDFLPRAYYRWTRAHDLRGFLNFTLARAPSSFAAAHNRTCRYRAFRDDDGHYSQTYWNLLAIRLAFVIVFEHVVFSVGRLLDLLVPDIPESVEIKVKREYYLAKQALAENEVLFGTNGTKDEQPEGSELSSHWTPFTVPKASQLQQ
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q6IWH7 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S53 | Phosphorylation | Uniprot | |
| S546 | Phosphorylation | Uniprot | |
| N809 | N-Glycosylation | Uniprot | |
| N824 | N-Glycosylation | Uniprot |
Research Backgrounds
Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylserine, phosphatidylcholine and galactosylceramide (By similarity). Does not exhibit calcium-activated chloride channel (CaCC) activity. May play a role in cell-cell interactions.
Cell membrane>Multi-pass membrane protein. Cell junction. Endoplasmic reticulum.
Note: Concentrates at sites of cell-cell contact (PubMed:17308099). Shows an intracellular localization according to PubMed:22075693 and PubMed:20056604.
Cytoplasm>Cytosol.
Specifically expressed in epithelial cells of the prostate (at protein level).
Belongs to the anoctamin family.
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